Functional magnetic resonance imaging as a prognostic tool after severe brain injury

People who have severe brain injuries that lead to a complete loss of consciousness are often admitted to an intensive care unit for aggressive life-sustaining therapies. Currently, there are no tools available to doctors to determine which patients will regain consciousness and have a good recovery. This makes discussions surrounding continuing treatment vs. withdrawal of […]

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Drive By Science

Annabelle’s research will focus on training image captioning datasets for the Drive By Science Project taking place in NASA Jet Propulsion Laboratory Mars Rover Artificial Intelligence (AI) division. The Drive by Science Project addresses a critical issue: the Mars Rover produces substantially more images than can be sent down to Earth, due to the limited […]

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Using artificial intelligence to screen children suspected with listening difficulties

The goal of this project is to create a cutting-edge screening tool for children with listening difficulties, which can have a profound impact on their academic performance, social development, and overall well-being. Despite the current assessment process, which is time-consuming and requires extensive training and experience, early identification and intervention are critical for these children […]

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Development of low-cost and lithium-metal stable halide solid electrolytes for high-performance all-solid-state batteries

Conventional Li-ion batteries using liquid electrolytes (LEs) are suffering from insufficient energy density and safety issues when used for the flourishing market of electric vehicles (EVs). Replacing LEs with solid-state electrolytes (SSEs) to fabricate all-solid-state lithium batteries (ASSLBs) has been regarded as an essential route to improve energy density and safety. Basically, a qualified SSE […]

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Conversion of biosolid to value added biochar via pyrolysis technology for PFAS elimination

Per- and polyfluoroalkyl substances (PFAS) are a very large family of persistent anthropogenic chemicals utilized in the manufacturing of industrial materials with non-stick and oil/water repellent properties, Teflon, and fire-fighting foams. Their use has resulted in their final dispersion in soil, groundwater, and surface water, causing adverse environmental and health effects. They are responsible for […]

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TAT-tagged active AKT1 variants for delivery to mammalian cells

The oncogenic kinase AKT1 is a prime therapeutic target, but its function cannot be easily researched as AKT activation in cells requires stimulation of cells with an unspecific growth factor that alters all cellular signaling. I designed a new method to deliver an already activated, phosphorylated AKT1 protein to cells that do not require the […]

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Examining the implementation of a free physical activity program for grade 5 children in London, Ontario

Physical activity is an important part of children’s development. However, a majority of Canadian children are not meeting the national recommendation of 60-minutes of physical activity. To counter this issue, London’s Child and Youth Network (CYN) developed the ACT-i-Pass Program, a physical activity program that offers free recreational programming to grade 5 children in the […]

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Development of a Digital Co-care System for the Management of Parkinson’s Disease

There is no cure for PD. Limitations of the current Canadian health care environment, compounded by the effects of the pandemic, have led to infrequent and imbalanced access to care for PwP, which may contribute to inaccurate assessments, incorrect medication dosages, and undermanaged disease symptoms. To improve the lives of PwP, a chronic disease management […]

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Improving the Crystal Morphology of Rufinamide by Experimental Structure Determination and Advanced Computational Approaches

Crystal shape and size are among the most important features of crystalline product that are prevalent in the pharmaceutical industry. Extremely fine and needle-like crystals pose various problems in the downstream processes including filtration, tableting, handling, and storage. Rufinamide is an anticonvulsant medication, and its most stable and therapeutically advantageous crystalline form shows notoriously undesirable […]

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