Development of the Metaplex Immuno-Oncology Platform – Immuno-Oncology Component

Current cancer immunotherapies, although highly successful, are complex to implement, costly, and only effective in small patient populations with specific cancer types. We propose to overcome these problems by developing small molecules to induce immunogenic cell death (ICD), a cancer cell death process that engages the immune system to recognize and eliminate cancer cells and […]

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Characterization and Techno-economic Feasibility of Physical Separation of Rare Earth Elements in Coals from East Kootenay Coalfields, British Columbia

Rare Earth Elements (REE) are a group of 17 elements in the periodic table including 15 lanthanides and two transition metals: Scandium and Yttrium. These elements are used in a wide variety of products including light-emitting diodes, wind turbines, fiber optics, lasers, batteries, guidance systems, and superconductors. Due to supply restrictions, the elements are classified […]

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Case Study Scenarios and Videos for Intercultural Competence Acquisition

To develop intercultural competence and further manage potential cultural-related challenges for international students and trainees, the intercultural competence acquisition experiences are explored in this study. The objective of this Mitacs project is to design and analyze users’ experience with six case study scenarios (Scaffolds, Scripts, & Videos) for training in intercultural competence. The scenarios correspond […]

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Advancing municipal natural asset management in engineering practice and beyond

Canadian local governments are seeking new strategies to deliver their core services in more financially and environmentally sustainable ways, including turning to infrastructure asset management as a key tool to manage infrastructure. Municipalities are increasingly recognizing that natural assets such as aquifers, forests, streams and foreshores can provide equivalent or better services to many engineered […]

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Retrofit of Switcher Locomotive: Clean Energy Hydrogen Fuel Cell/ Battery Hybrid (Hydrail) with Innovative High Density H2 Storage

The H2M project, with the assistance of University of British Columbia Okanagan, will demonstrate a scaled down fuel cell powered rail locomotive (Hydrail) (250 horse power) and solid-state hydrogen storage retrofit solution on a Southern Railway of BC (SRY) diesel-electric switching locomotive. If the scaled down trial is successful, the project will proceed to scale […]

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Health Records over Blockchains

It is hard to understate the critical role access to a patient’s comprehensive medical history plays in diagnosing (and treating) patient illness. For a doctor, knowing the latest prescribed drugs of his patient might, for example, point directly to the cause of an illness — which might be just a drug side effect. Yet patients […]

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Feasibility assessment and development of knowledge, technology, and tools for mercaptan natural gas odorant monitoring

FortisBC Energy Inc. is exploring novel technologies and methods for mercaptan monitoring to detect natural gas leakage in industrial, field, and household settings. Since commercial mercaptan detectors are bulky and expensive, there is a need for low-cost and miniaturized mercaptan detectors. The proposed project will lead to the development of a handheld mercaptan detector which […]

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Novel sensing and actuating technology for gaseous fuel systems

The participants listed below confirm that the information presented accurately reflects their intention to apply to the Mitacs Accelerate program. The participants have also agreed to set in place an internship based upon the attached proposal. The participants acknowledge that they have read, understood and agreed to abide by and uphold the Project Responsibilities applicable […]

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Development of MCT4-targeting small molecule inhibitors for management of castration-resistant prostate cancer

Late-stage, therapy-resistant prostate cancer (PCa) remains a difficult-to-treat disease that urgently needs better therapeutics. Advanced PCa cells use glucose (sugar) differently than normal cells, substantially increasing lactic acid secretion into the surrounding environment. This supports cancer growth in numerous important ways, including helping PCa avoiding destruction by the patient’s immune system. One critical protein involved […]

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Mechanisms of Antibacterial Activity of Kisameet Clay, A Natural Clay Mineral from British Columbia, Canada

The discovery and development of antimicrobials as therapeutic agents has transformed modern medicine. However, their further mass production, global distribution, and gross misapplication have resulted in escalating emergence of multi-drug resistant (MDR) bacteria worldwide. Given the limited arsenal of antimicrobials available to combat MDR bacteria, there is growing apprehension about the threat posed by “superbugs” […]

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