Prototyping and Industrial Testing of Novel Non-Consumable Thermocouples/Sensor Holders in Molten Steel

Secondary metallurgy is the most value adding step in the steelmaking process. As more sophisticated steel grades are developed, better process control is required to adjust and monitor properties of molten steel in secondary metallurgy. Improved process control also serves to increase productivity and profitability of steel mills. In steelmaking, process control is achieved through […]

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Chemistry, manufacturing, and control (CMC) assessment of Manganescan

To design effective and patient-specific cancer therapy, sensitive detection of relapse and distant metastases by non-invasive medical imaging is essential, for which MRI offers tremendous potential due to wide availability of the equipment in clinic and avoidance of ionizing radiation. Although gadolinium-based contrast agents are the most frequently used for MRI, they are associated with […]

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PATH: Program to Accelerate Technologies for Homecare

Most people would like to continue living in their own homes as they age. A new ecosystem is needed to enable home health technologies to be developed, tested and successfully commercialized. This will require a program that provides a low-cost way for developers to test their products before introduction to the market. Therefore, in our […]

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Enhanced Modelling of Exfiltration Events in Sun Life Cybersecurity Data

Theft or loss of sensitive data is a growing concern for companies who may suffer losses of consumer confidence, market valuation and intellectual property when large amounts of data are stolen. In this research project we will use an enhanced “screen and review” approach to combating exfiltration in a large data set of activity logs […]

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Detargeting Protein-Protein Interactions For Cellular Design Applications, Using 3D Structure-Based Deep Learning Models

Rational protein design has had a tremendous impact on pharmaceutical, agriculture, and chemical industries over the past 30 years, by focusing exclusively on individual proteins and their intrinsic activities. The next generation of protein design tasks will seek to modify function inside living cells, competing and interacting directly with pre-existing cellular machinery. Modifying systems in […]

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COVID-19 and ultraviolet-C disinfection of porous and non-porous surfaces: modeling, validation, and performance of new devices

The COVID-19 pandemic led to an increased demand for disinfection solutions, including ultraviolet C (UVC) light technologies. UVC works by inactivating microorganisms and show a strong potential to break the chain of infection in hospitals and public settings. CleanSlate and the University of Toronto are exploring this potential by characterizing how the virus that causes […]

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Performance Based Design of Viscoelastic Coupling Dampers in Mass Timber Buildings

Viscoelastic Coupling Dampers (VCDs) have been developed over the past 15 years at the University of Toronto and by Kinetica for use in multi-storey buildings constructed with conventional construction techniques (steel and concrete). It has been shown the VCDs improve the wind and seismic performance of these buildings, leading to safer, higher performing and more […]

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Automated Driver Drowsiness Control Technology Using Artificial Intelligence-based Decision Support System

The main purpose of this project is to develop the methodology to detect and predict driver drowsiness at the early stages using physical and physiological variables. A feasibility test is conducted to evaluate the accuracy and performance of the proposed methodology. The existing databases are leveraged to extract the required data. Signal processing, image processing, […]

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Point-of-care breath analyzer for early-stage disease diagnosis

As the third documented emergence of an animal-to-human coronavirus during the past two decades (Severe Acute Respiratory Syndrome in 2002, Middle East Respiratory Syndrome in 2012), the current pandemic and near-certainty of future epidemics demands intensified surveillance and proactive screening. Definitive therapy for novel Coronavirus Disease 2019 (COVID-19) is likely at least half a year […]

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