Improved data driven sgRNA design for use in bacteria

CRISPR/Cas9 is a promising tool for genome engineering in bacteria, but it’s limited by inconsistent accuracy. Though some studies have been conducted to understand why this inconsistency occurs, many important biological features have not been explored. Moreover, computer based attempts to predict accuracy have suffered from these knowledge gaps. This is due mainly to the […]

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Dynamic Modeling of Hydrate Formation and Dissociation in the Presence of Thermodynamic and Kinetic Hydrate Inhibitors

This project supports a joint industry project (JIP) involving operator companies active in offshore Newfoundland and Labrador. The JIP is supported through a contract with Petroleum Research NL (PRNL). The project aims to remove obstacle to cost effective developments from marginal oil fields in Atlantic Canada. This will be through developing strategies and techniques to […]

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Simulation and modifications of an industrial scale dehydrator

CanDry is currently in R&D stage developing a dehydrator for drying organic and in-organic materials. A prototype is built for testing purposes which will help to design a good quality product. For modifying the design of prototype, we need to simulate the electromagnetic behaviour of the system and run multiple tests to compare the simulation […]

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Skill – An AI-generation resume standard

Skill is an open-source standard format for resume writing that is optimized to be processed by AI systems. It can remove the hassle and stress of fully expressing themselves from job seekers and eliminate the hassle of finding the best candidate from employers. As AI systems grow more popularity in different fields, Skill will provide […]

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Risk Assessment of Riverbank Stability Subjected to Construction Induced Vibrations

The stability of riverbanks has always been a concern for land-use planners, stakeholders as well as the Cities around the world. Construction activities can generate different types of dynamic waves and vibrations. Operations such as blasting, pile driving, dynamic compaction of weak soils, and machines with impact loads such as forge and drop hammers are […]

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Impact of dark chocolate consumption on glucose levels of people with diabetes

Blood sugar levels increase after the consumption of food. Especially in sugary foods such as candy or chocolate, this increase in blood sugar will be more pronounced. In individuals with diabetes, who may require tracking of carbohydrates and food or injection of insulin following a meal, foods such as chocolate are suggested to be avoided. […]

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An Investigation of Potential Market Entry for Novel Medical Devices ina Pandemic Environment

Currently, it is difficult to obtain market share in the medical device market. Furthermore, a lack of resources by small companies with disruptive technologies can prove to be detrimental to establishing market share. This huge hurdle thus discourages innovators from commercializing their life-saving technologies especially in a pandemic situation. This project will focus on the […]

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Assessing temporal and spatial patterns of bowhead whale presence and underwater noise in the western Canadian Arctic

Understanding when and where bowhead whales occur is ecologically, culturally and politically important in the context of a rapidly changing climate, with some of the greatest impacts happening in the Arctic. Decreases in sea ice allow for increased shipping and its associated underwater noise in one of the last acoustically pristine habitats in the world. […]

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Stress Detection for Plants Grown in a Controlled Environment

Precision agriculture is the technique to replace traditional farming methods to sustainably improve crop productivity and ensure food security without adversely impacting the environment. Pure Roots Holdings Canada Inc. is managing an ecosystem that encapsulates 0.4 acres of the effective farming area into a modular grow room called AeroPod. AeroPod provides an automated, modular, mobile, […]

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Effect of Diesel Exhaust Exposures on the Respiratory Microbiome in COPD Airways

Some of the bacteria present in healthy lungs protect the lung against harmful germs. Studies have shown that people with lung diseases often lack these “good” bacteria in their lungs. Our team has been demonstrated that breathing polluted air causes lung inflammation, which can make it hard to breathe, especially for people who have lung […]

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A rational data-driven probabilistic approach for assessing the condition and performance of RC structures

A variety of alternative strategies have been developed for increasing the service life of reinforced concrete structures exposed to corrosive environments. An optimum design or repair strategy requires not only an estimate of upfront costs, but also the means to compare all associated costs against the potential extension to the life of the structure. Unfortunately, […]

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Mobilizing the beneficial microbiome of Ontario wheat against Fusarium

Scientists have been interested in the effects that microorganisms have on their host plants for over a century, however, recently researchers have been able to better tackle these questions with the advent of new technology. In particular, beneficial microorganisms associated with roots can increase crop resiliency against disease, pests and extreme weather events, making this […]

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