In the present project, we aim to contribute to the investigation of the potential use of botulinum toxin (BoNT-A) injections in the brain for the treatment of PD symptoms in the long-term. Particularly, we pretend provide evidence that allow optimize the use of BoNT-A, defining optimal concentrations and periodicity of treatment, as well as the […]

The aim of the project is to design and test different chemical derivatives of betulinic acid as a treatment for cancer. It is well known that betulinic acid is able to specifically kill cancer cells, and so we have developed several derivatives to improve biochemical properties such as solubility or biodistribution but maintaining the toxicity […]

During the production of pulp, in the pulp and paper manufacturing process, one component of the tree is extracted into the pulping liquid. This component, called lignin, has potential value as an important renewable material for adhesives, fibre, and coatings. The proposed research has the focus on evaluating the pulping liquid for all of its […]

The use of hybrid distributed energy resources (HDERs) has grown rapidly during the last decade as a way to reduce the stress placed on the utility grid by society’s ever-expanding power consumption. They consist of fossil fuel generators, battery energy storage systems, and renewable energy systems and can be designed to interact with the grid […]

In the first year of the proposed project, we will explore and optimize the application of environmentally friendly solvents for organosilane adhesion promoters that are used in the production of HSS by Canusa-CPS. In the second year, the shelf-life and lifetime of such products will be investigated using accelerated testing procedures. The results of the […]

Agricultural runoff transports nutrients such as phosphorus (P) and nitrogen (N) that act as environmental pollutants in fresh and coastal marine ecosystems. Both chemical fertilizers and animal manure release substantial P and N to runoff and leaching despite current conservation efforts. While recent research has shown that struvite could be a viable P supplement for […]

Corona Virus 19 creates adverse effects on the global health system leading to economic crisis. Although trials to develop vaccines are underway, it would take a while for the general public. Wearable sensors have been receiving increased attention toward monitoring the wearer’s well-being and playing a significant role in the healthcare industry. The upper respiratory […]

As the world finite supply of fossil fuels diminishes, viable alternatives are needed to empower the transportation, heating, and industrial needs of modern civilization. Lignocellulosic ethanol promises a means to transform abundant plant wastes into an energy-dense, carbon-neutral liquid combustible, compatible with current infrastructure. Unlike the first-generation biofuels derived from corn or sugarcane, lignocellulosic ethanol […]

The process of setting surgical schedules in a modern hospital operating room suite is complicated. Scheduling surgery involves coordinating two separate but inter-related service distribution channels, namely, elective surgery operations and emergency surgery operations. Elective surgical cases are selected from a broad range of diagnostic categories and are scheduled in advance into surgical time that […]

The current COVID-19 pandemic has burdened the healthcare system and disrupted economies worldwide. One method of combating this pandemic is through serological testing, which can determine who has been exposed to the virus and developed an immune response. This is particularly important for front-line healthcare workers as the test would identify individuals who are potentially […]

As mine pit slope become higher, the implications of accurately predicted slope angles becomes greater for worker safety, environmental impact and economics. Over the past decade, data analysis and computational methods have resulted in significant research developments in this area. Utilizing these some of thee methods requires a high level of field data and large […]

In beer manufacturing, the liquefaction and saccharification process utilizes heat, alkaline and acid washes to break down complex sugars into wort (simple sugars) leading to destruction of desirable bioactive compounds. Beer manufacturers are keen to use green technology and non-starch plant materials from agri-food by-products. Province Brands has developed its proprietary methods for brewing from […]