NUR77 AND RXR: NEW TARGETS IN DRUG-INDUCED DYSKINESIA

Drug-induced dyskinesia is a debilitating side effect induced by anti-parkinsonian and antipsychotic drugs. Frequency can reach 80% in Parkinson’ disease and around 50% in schizophrenia patients treated with typical antipsychotics. Treatments for dyskinesia currently available have a very limited impact and generate important side effects. We have identified a new pharmacological target that may offer […]

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Developing durable and electrical conductive concrete composites for Quebec

This project focuses on the development of Electric Conductive Concrete (ECC) pavements which can efficiently reduce the cost of snow removal of Quebec. Recent research has proven that temperature regulated pavements can melt snow and ice. By taking advantage of all latest technology in conductive inclusions, the project aims will develop an optimized ECC mix […]

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Development of a Raman probe for the on-line determination of pulp properties

Canadian northern bleached softwood kraft (NBSK) market pulps set standards worldwide for fibre strength, length, fineness and uniformity. These characteristics add unmatched strength and durability to finished goods, and this drives a high international demand for NBSK pulp. However, competition has increased the price-performance pressure on Canadian suppliers. The Canadian pulp industry must innovate to […]

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Degradation Assessment for Critical Assets in Power Generation

Degradation assessment for critical assets in power generation has great significance for power industry. Existing degradation assessment models failed either in combining the multimodal condition monitoring data or in removing time-varying working condition influences, resulting in inaccurate and/or unreliable degradation assessment results. In order to achieve robust and accurate degradation assessment for power generation critical […]

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Using PET/MRI to improve current pre-clinical biomarkers in cancer

Treatments that involve activating a patient’s own immune system, immunotherapies, are becoming important cancer therapies. Unfortunately, doctors don’t always know the best way to combine these therapies to best treat patients and the current tools they have to evaluate treatment success don’t work well for immunotherapies. Molecular imaging, particularly magnetic resonance imaging (MRI) or positron […]

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Cost-Benefit Analysis of Cardiac Arrhythmia Care Pathways Project

The interns will be engaged to to identify potential target patients and provide a cost-benefit analysis of various forms of CA care pathways, with a focus on identifying the strengths and weaknesses of implementing an e-health system compared to the current model of care.The target patient analysis will be conducted through the development and use […]

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Study the bond strength of adhered manufactured stone veneer units and setting bed mortar at different temperatures and different cycles of freeze-thaw

The bond between adhered manufactured stone masonry veneer units and the setting bed mortar will be studied. It will involve testing shear, and tensile bond on small samples. Samples will consist of 2 types of adhered manufactured stones; two types of setting bed mortar (Type S, and modified dry-set cement mortar); and two types of […]

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Trends, opportunities and adaptive strategies in the natural fiber market

As the consumption of cigarettes declines in North America and Europe market, a company that specializes in manufacturing specialty papers is seeking new opportunities with its natural fiber productions. This research intends to identify new market trends and opportunities for natural fibers in the competitive environment; provide a comprehensive analysis in worldwide natural fiber industries; […]

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Somatostatin signalling and diabetes

The prevalence of diabetes is growing rapidly and currently, over 60 million people worldwide use insulin treatment to manage their diabetes. However, insulin treatment can result in hypoglycemia or low blood sugar levels. To date only retroactive treatments are available to treat hypoglycemia, which affects an individual’s quality of life and increases the likelihood of […]

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Oncolytic HSV-1 (oHSV-1) for treatment of prostate cancer

This project is to use genetic engineered “cold-sore” virus to treat prostate cancer. The virus is engineered to reduce its toxicity to normal tissues but can specifically attack and kill tumour cells. Meanwhile, the virus releases a group of anti-tumour immune stimulating factors to activate immune system to eliminate prostate tumour. This project will use […]

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Perpetual Nomads: an exploration of indigenous narratives and imagery through contemporary and experimental mediums

The goal of the Perpetual Nomads project is to make illustration depicting many indigenous and environmental issues through traditional art media and digital media. The team will be exploring the viability of creating Mixed Reality interactive experiences to increase the awareness, empathy, egalitarianism and environmental concern in users through these illustrated narratives. Since people use […]

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