In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem […]

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Exploring home range and habitat use during the breeding season of the Bicknell’s thrush (Catharus bicknelli) in New Brunswick Clear-cuts

The Bicknell’s thrush (Cathurs bicknelli) is a rare songbird with the most restrictive breeding range in North America. The Bicknell’s thrush spends its summer months breeding in high elevation, stunted growth forests – a habitat that the species specializes in. In New Brunswick, there has been a documented population decline of 11.5% per year since […]

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Context-Aware Advertising Language Analysis and Modeling in Internet Display Ads

Internet display advertising is a substantially growing industry, where advertising spots are dynamically allocated according the product characteristics and the target audience. This is commonly seen on Facebook or Google. However, accurate audience targeting is still an enormous challenge in practice, and often evokes frustration for advertisers and users. However, with the rapid growth and […]

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Identifying the drivers of polar bear-human interactions

Polar bears are curious, and that curiosity often leads them into conflict with people. Park and wildlife managers across the Arctic need to understand why polar bears approach people and whether they do so because of human activities, a lack of sea ice, or a combination of both of these factors. Currently, this is not […]

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Synchrotron investigation of water distribution in fuel cells and correlation to properties and performance

Polymer electrolyte membrane (PEM) fuel cells convert hydrogen and oxygen into electrical power through an electrochemical reaction, producing water and heat. These fuel cells have been considered for automotive powertrain applications. In this proposed work, a set of varying PEMFC materials will be investigated to advance the performance of PEM fuel cells. The fuel cells […]

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Development of a simulation model for prediction of performance of an anesthesia circuit using a novel CO2 separation system

Anesthesia is delivered to patients in vapour form, supplied via Mechanical ventilation in closed loop anesthesia circuit. This necessitates the removal of the carbon dioxide (CO2) produced during respiration. Currently, anesthesia circuits use granulate-based CO2 absorbents that react with CO2 to remove it from the gas stream. However, anesthetic vapours also react with the chemical […]

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Fundamental understanding of brewing phenomena and shelf-life extension of single-serve coffee – Year two

Brewing of premium coffee in single-serve capsule is challenging due to many design and machine constraints. Moreover, parameters that affect the brew quality are not fully understood. By collaborating with Mother Parkers Tea and Coffee Inc., this project will systematically evaluate the brewing parameters on the physical and sensorial properties of drip and espresso coffees. […]

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A novel scaffold for tympanic membrane repair – Year two

The ability to hear, and the quality of our hearing, depends on the health of the eardrum. Eardrum perforations due to diseases and accidents can be treated using grafts, such as autologous grafts, allografts and xenografts. These replacements suffer from various limitations such as donor site morbidity, long operation time and healing time, and risk […]

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Comparative effectiveness, and network meta-analysis of pre-insulin oral hypoglycemic drugs in the treatment of type II diabetes

The proposed project is two-phased. The first phase involves a study that will use specialized research analysis techniques to compare the effectiveness of pharmaceutical drugs used to treat type II diabetes and to identify if a group of drugs are producing similar benefits in terms of controlling the disease. The applicant’s clinical and epidemiological background […]

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Education in the field; using behavioral wildlife research to inform the interpretive program of an eco-tourism operation – Year two

Knight Inlet Lodge is an eco-tourism resort specializing in grizzly bear viewing, and caters to both national and international clients. The business requires research to improve their interpretive program by informing guide naturalists on the function of observed bear behaviour. Research is required to: 1) assess the relatedness and movements patterns of regularly observed bears, […]

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