The politics of clinical trials in a pandemic: The role of the blood service indeveloping a treatment for COVID-19

In response to the COVID-19 pandemic, hundreds of clinical trials are currently ongoing to evaluate the effectiveness of convalescent plasma derived from individuals who have recovered from COVID-19. As a licensed plasma collector for transfusible plasma and the National blood operator (outside Quebec), Canadian Blood Services has consequently taken on a unique role in several […]

Read More
Exploring the Potential of Convalescent Plasma Therapy as an Intervention in the Pandemic Response

Convalescent plasma–used for over a century as the first treatment option in outbreaks caused by novel pathogens. The therapy involves transfusion of blood plasma from recovered donors, which contains antibodies, that can prevent or treat infection in recipients. Convalescent plasa therapy has been observed empirically or in small studies to confer passive immunity to susceptible […]

Read More
Novel Cell-surface Engineering Methods to Increase Immune-tolerance of Allogenic Cell Transplantation

Blood transfusion is required for surgery, for the treatment of traumatic accidents and for patients with disorders that require lifelong transfusion therapy. However, when patients receive “mismatched” blood transfusion, their immune system will attack and destroy red blood cells with surface sugars and proteins that differ from their own. This results in massive immune responses […]

Read More
Blood product demand forecast modeling using clinical predictors

Blood transfusion is one of the most crucial and commonly-administrated therapeutics worldwide. The need for more accurate and efficient ways to manage blood demand and supply is an increasing concern in many countries. Building a technology-based robust blood demand and supply system that can achieve the goal of reducing the costs of wastage and shortage, […]

Read More