Spinal Cord Stimulation utilizes a pacemaker like device, to deliver electrical impulses to the dorsal column of the spinal cord via an electrical lead placed in the epidural space.The electrical stimulation saturates the large nerve fibers with electrical noise masking the sensation of pain by creating a gentle tingling sensation in the area of pain. […]

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. There is a pressing need to discover novel targets to enable precision health, promote new therapeutic discoveries, and […]

COPD is a common inflammatory lung condition that is characterized by airflow limitation and symptoms of cough and shortness of breath. Globally, it affects 384 million people and is responsible for ~4-7% of all deaths. Longitudinal genome-wide association studies (GWAS) are needed to unravel the molecular determinants of dynamic quantitative traits underlying COPD, such as […]

Organs-on-chips are miniature devices mimicking aspects of human organ functions. Their main purpose is to serve as an alternative to animals as a testing ground for drugs, pollutants and toxins to see their effects on organs. The lung-on-a-chip device, which is the focus of this research, has been used to demonstrate how air-born nanosized particles […]

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, which is characterized by shortness of breath and progressive loss in lung function, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. Therefore, there is a pressing […]

COPD is a progressive inflammatory airway disease characterized by persistent and progressive airway inflammation. It is a major cause of global morbidity and mortality and is predicted to become the third leading cause of death by 2020. Biomarkers may be useful for diagnosing disease considering that the usually used lung function measures have poor correlation […]

Chronic Obstructive Pulmonary Diseases (COPD) is a lung disease that cause a lot of suffering to the Canadian population. To accelerate the drug discovery process, an old blood pressure lowering medication was tested to block the progression of COPD. A patient study showed that the old medication did provide some protective effect to the lung […]

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, and one that affects 2.6 million Canadians and 380 million people worldwide. Although the disease affects a large population worldwide the therapies used for treatment remain imprecise. With the lack of disease modifying therapies there is a pressing need to discover novel targets […]

Chronic Obstructive Pulmonary Disease (COPD) is a common illness that affects millions of Canadians, yet there are no effective therapies to treat it. Genes play a role in COPD development, and our proposal aims at identifying those genes in lung tissue that cause the disease. The Providence Airway Centre is very committed at helping COPD […]

Chronic Obstructive Pulmonary Disease (COPD) is a progressive, debilitating, chronic respiratory disease that affects 600 million people worldwide and is responsible for 3 million deaths worldwide each year. Given the recent advances in artificial intelligence (AI) and the availability of large datasets from both the public and private sectors, our project applies AI to analyze […]

Chronic obstructive pulmonary disease (COPD) is an important global health problem afflicting 384 million people and causing 3 million deaths worldwide each year. Currently, there are no effective therapies for COPD patients. In this proposal, we are developing a novel technology that will both monitor the severity of disease in COPD patients, and allow researchers […]

There are 2.6 million Canadians with Chronic Obstructive Pulmonary Disease (COPD). COPD is a disease characterized by progressive loss of lung function that leads to shortness of breath, poor quality of life, reduced productivity, emergency visits, hospitalizations and mortality. The World Health Organization estimates that COPD will be the 3rd leading cause of death worldwide […]