Osteoinductive, osteogenic and angioinductive potential of intramuscular injected genetically modified human umbilical cord perivascular cells

The loss of bone is a massive burden on the health care system and severely impacts the quality of life of several hundred million people. The need for alternative strategies to replace or regenerate bone tissue is overwhelming. We are proposing a completely new approach to the engineering of bone using a “cocktail” of genetically […]

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Human umbilical cord perivascular cells as cell therapeutics for biodefense and immunomodulation

Mesenchymal stromal / “stem” cells (MSCs) are found in adult tissues such as bone marrow and fat and also in neonatal tissues such as the placenta and umbilical cord. Among these sources, Human Umbilical Cord PeriVascular Cells (HUCPVCs) are the richest source of MSCs described. Importantly, they possess immunomodulatory and immuneprivileged properties which enable them […]

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