CT Image Optimization and Radiation Dose Reduction Strategies

  Advances in computed tomography (CT) have facilitated wider utilization and introduction of new clinical applications associated with high patient radiation dose. Subsequently, there is increasing concern for the potential long term cancer induction risks associated with increasing CT utilization bparticularly in younger women. Therefore, there is an urgent requirement to establish diagnostic CT protocols […]

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Optimization of CT Coronary Angiography for Vessel and Plaque Analysis

The aim of this grant proposal is to address the challenges with current CT Coronary Angiography (CTCA) utilization with a comprehensive series of interrelated but well-defined research themes. This non-invasive technique has facilitated in the detection of significant coronary artery disease and vulnerable plaque. However, the quality is limited to the physicality of the patients […]

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Novel application of deformable image registration using Computed Tomography for early diagnosis of lung parenchymal disease: focus on lung fibrosis

We aim to optimize advanced Computed Tomography (CT) imaging to provide non-invasive and accurate assessment of early lung fibrosis. Lung fibrosis causes inflammation and scarring of lung tissue and can be progressive, even fatal. Currently, detection of lung fibrosis relies on relatively insensitive tests, such as pulmonary function tests and static lung CT. Alternately, microscopic […]

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