Shotgun mass spectrometry-based proteomics has emerged as the most powerful approach to comprehensively analyze proteins in a biological sample over the last few years. This technology will play a key role in the predictive, preventive, personalized, and participatory medicine design. Correct peptide identification from a tandem mass spectrum is the crucial step to determine the target protein sequence and […]

  Shotgun mass spectrometry (MS) has emerged as a powerful technology for large-scale proteomic analysis recently. By measuring thousands of peptides in a prepared sample, health researchers can gain insight into the complex disease pathways, which can be used for diagnosis and treatment. A crucial problem in the current MS experiments is that not every peptide can be effectively […]

  UV disinfection technology is recognized as a potent tool for the disinfection of water and wastewater. A recent study of wastewater treatment technologies concluded that UV and ozone treatment are the most advantageous advanced technologies for disinfection of pathogens. Trojan Technologies Inc. (Trojan), the industry partner, based in London, Ontario, Canada, is the world leader in the development, […]

  Toronto’s CN Tower is the world tallest freestanding tower structure. Built between 1973 and 1975, this giant communication and observation tower represents the extensive design process that lasted six years. The structural design of the Tower was one of the major challenges of design process. The structure has been designed based on the latest […]

This project is designed to determine best management practices for a devastating disease of turfgrass that is currently controlled primarily by multiple fungicide applications. By assessing appropriate cultural practices aimed at reducing disease development it is our hope that we can reduce fungicide applications for this disease. In addition, the development of a rapid and simple diagnostic tool would […]

  The ability to make safety-related decisions and to demonstrate compliance with regulatory or safety limits is of great importance in the nuclear industry. For example, we may be interested to assess whether a component (such as the pressure tube which carries fuel) has undergone physical changes that have exceeded its allowable limits (e.g., the […]

  The Semantic Web offers a tantalizing new opportunity to share knowledge that is formally represented. While general visualization strategies for linked data are the subject of many current investigations, certain relations have a well understood meaning which could lead to custom visualization strategies. Our research proposal consists of three parts: (1) surveying the kinds […]

  Transfusion medicine in Ontario faces two challenges, how to reduce the potential for errors, and how to reduce the use of blood products when blood supply is low. New technology such as electronically controlled blood fridges is suggested for tackling these two challenges but little is known about their actual impact on errors or blood usage. In view […]

  This project will focus on very high‐speed communication along electrical links. Key to these links are the integrated circuits required to serialize and deserialize many parallel data streams into a single data stream at rates exceeding 1 Gb/s (i.e. SerDes). We will collaboratively explore the signal processing and circuits required to perform these implement SerDes robustly in […]

  The proposed research is directed at determining the effect of amino acid (AA) infusions on the milk synthetic regulatory proteins found in the mammary gland of the lactating dairy cow. Previous research in the area has shown that proteins called eukaryotic initiation factors (eIF), which synthesize proteins through mRNA translation, are a regulation point […]

  Supra – nutritional consumption of organic selenium (Se) reduces the incidence and progression of several types of cancer. The organic Se content of with cows’ milk can be increased by supplementing cow diets with organic Se. In vitro preliminary data suggest that Se supplementation of cows may improve the persistency of daily milk yield, […]

  Feather meal is an economical protein-rich feedstuffs produced from wastes generated by the poultry processing industry. The partner organization, a fish feed manufacturer based in Ontario, would greatly benefit from the accurate characterization of the nutritive value of feather meals for different fish species raised in Ontario. Inclusion of feather meal could significantly improve cost-effectiveness of fish feeds […]