Castration-resistant prostate cancer is a late stage disease and many people die of it due to lack of effective therapeutic drugs. In the current project, we propose to develop new therapeutic drug a to specifically target CRPC’s common weak points, which are MCT4 and eIF4E gene’s proteint products that play very important roles in regulation […]

In this grant, the consortium will develop new methods to characterize nanoparticles prepared with a proprietary polymer. This study will enable the fabrication and characterization of better performing nano-sized particles encapsulating therapeutic molecules, commonly called nanomedicines. This study will allow to monitor how the polymers self-assemble into nanoobjects under different conditions, and to study how […]

In a prior project, promising results were obtained showing the possibility of using graphene/polymer composites as advanced materials having superior properties than the conventional carbon black loaded polymers. The composites obtained presented electrical conductivities with values of about 10-2 S/m when the percolation threshold was exceeded, an increase of more than 12 orders of magnitude […]

Nowadays, automotive companies are seeking to use prospective robust, light-weight, anti-corrosive and cost-effective composites such as fibre reinforced polymer (FRP), instead of traditional materials like steel or aluminum alloy, to make their products more competitive in the market. The sponsor company in this project, Litens Automotive Group, is investigating the feasibility of adopting FRP to […]

Cochlear implants are surgical implanted devices that allow deaf people to recover some form of hearing and understand speech, but current devices are limited, and the consequences of these limitations have not been fully explored. For example, there is a growing consensus that hearing loss interacts with cognitive systems. Yet, relatively little is known about […]

Mysis diluviana, a shrimp-like crustacean, is an invasive species in Okanagan Lake. As part of a strategy by the BC government to reduce the impact of this species on the natural lake ecosystem, Piscine Energetics Inc. has been harvesting Mysis from Okanagan Lake since 2000 and retails the harvested Mysis as fish food to the […]

Bacterial pathogens of importance to animal health and food safety have major and global impacts on agriculture and food industries. There has been an increase in bacterial resistance to antimicrobials, and antibiotic use in livestock and poultry has been questioned due to likelihood of increased antimicrobial resistance. Alternative strategies to contend with bacterial pathogens within […]

This project uses a large amount of geographic information and advanced computing technology to re-evaluate the influence of climate on the productivity of Saskatchewan’s agricultural land, which represents about 40% of all the cropland Canada. The intern will combine digital maps of soil, land use, crop yield, elevation, and historical weather observations. By exploring the […]

The proposed Mitacs program will provide internships for six graduate (thesis-based MSc and PhD) students, and two Post-Doctoral Fellows (PDFs) in a competitive R&D environment at the Thunder Bay Regional Health Research Institute (TBRHRI) – Canada’s newest health research institute. Interns will be involved in research projects which aim to develop and commercialize the next […]

The University of Saskatchewan (U of S) specializes in developing and building instruments which make detailed measurements of the composition of the atmosphere. These measurements provide a key link to the Earth’s climate system and are important in estimating and predicting air quality. The U of S has partnered with ABB Inc. to develop an […]

Electrochemical water splitting into hydrogen and oxygen gas is a technology of growing importance in the clean energy storage and conversion sector. While this technology has been operating successfully for decades using liquid electroytes, emerging technology uses membranes to provide physical separation of the cathode and anode compartments and thereby separation of the product gases, […]

The generation of functional ?-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is a strongly investigated area. Recent scientific breakthroughs have enabled derivation of large quantities of human pancreatic ?-like cells in the laboratory, but the protocols are currently not consistent or optimized for cells of various […]