Advanced differential mobility mass spectrometry with electron capture dissociation for the characterization of therapeutic proteins – Year two

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

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Detection of Mental Health Conditions from Textual Device Communication

Research into child safety applications using Artificial Intelligence (AI) methods is a new area of investigation. SafeToNet is continuing to develop AI monitoring tools together with a team of researchers at the University of Ottawa. These tools, when used over time, will take advantage of outgoing text-based communications from devices to detect the early onset […]

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Developing Intelligent Approaches for Factories of the Future – An intelligent strategy for robotic part inspection in advanced manufacturing – Year two

This project explores incorporation of artificial intelligence tools for advanced control techniques in order to improve quality on industrial production lines. Particularly, the novelty of this project suggests the use of the recent embedded computer systems and icloud computer assistance. This strategy is currently used for commercial products (i.e., application related to communication). However, this […]

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Privacy Preserving Federated Learning – Year two

By virtualizing all the various appliances in the network, Network Function Virtualization (NFV) became a key enabler for the coming 5G infrastructure and nowadays a major shift is under way bringing an evolution to cloud-native NFV. In the latter operational model, applications are decomposed into microservices running inside containers to enable automated installation, configuration and […]

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Improving energy system planning solutions by accounting for inherent uncertainties through robust optimization

More and more distributed energy resources (smart loads, self-generation, electric vehicles, etc.) are installed directly at the customers.  This causes fluctuations in the distribution network that can reverse the power flow or increase the cold pick-up effect. The infrastructures in place have not been designed for this new reality and they must be adapted accordingly, […]

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Techno economic assessment of state-of-art innovative fast pyrolysis solutions in bio-economy processes

The present project will evaluate the techno-economic and environmental performance of an Integrated Biorefinery System that employs an innovative state-of-art fast pyrolysis processes for the production of bio renewable fuels in the bio-economy. A systematic design methodology will be defined using state-of-the-art process systems engineering tools which include market analysis, techno-economic assessment, cost accounting, energy […]

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Going On-line with Cognitive Rehabilitation: Testing and Implementing Web-based Goal Management Training at Clinical and Commercial Levels

Goal Management Training® (GMT) is a Baycrest cognitive intervention that has been studied extensively, applied clinically, and manualized into kits for clinicians that have been commercially available since 2012. GMT targets executive functions, a collection of higher-level abilities involved in planning, organization, strategy, and inhibition. Executive impairment can be seen in normal aging as well […]

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Optimization of astaxanthin production in large-scale cultivation of microalgae by utilizing industrial CO2 emissions – Year two

Haematococcus pluvialis is a green microalga that concentrates the compound astaxanthin, a commercial product with nutraceutical, pharmaceutical, cosmetic, aquaculture, and food applications. Astaxanthin is a carotenoid pigment with high antioxidative activity, used as a feed additive to provide a characteristic pink color to salmonids and shrimp, as well as a human nutraceutical providing protection from […]

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Molecular Characteristics of Cellulose and Cellulose Derivatives – Year two

Cellulose is a commercially important biopolymer. Due to its abundance, biocompatibility and renewability it has shown important commercial applications in food, pharmaceuticals, biomedical. Depending on the origin and the processing methods used, the resulting fiber dimensions, structure, crystallinity and molecular weight (MW) can vary over a broad range. MW is one of the most important […]

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Advancement of bio-processing technology for ginseng polysaccharides: a model for value-added medicinal plant polysaccharides development – Year two

This proposed project focuses on American ginseng (AmG), a natural herb native to Canada that has been used as a traditional medicine for many generations. Southern Ontario has become the World’s largest producer of AmG with annual sales of over $400M at the farm gate. Polysaccharides (PS) are a major active component of AmG showing […]

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Part of the water, part of the land’: Developing Indigenous water legislation for Carcross/Tagish First Nation – Year two

The protection of water is a priority for Carcross/Tagish First Nation (C/TFN) and revitalizing Indigenous legal and governance systems is fundamental to advancing Indigenous approaches to water governance. While the citizens of C/TFN have governed the waters and lands within their traditional territory since time immemorial, their Tagish and Tlingit legal orders have been disrupted […]

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