Optimizing medical marijuana: developing genetic and chemical resources to improve thequality and quantity of cannabinoid metabolites in Cannabis sativa L strains Year Two

Determine how cannabinoid metabolites and their relative abundances differ among marijuana strains. Post Doctoral Fellow Name: Teagen D Quilichini Cannabinoids are synthesized and accumulate in Cannabis plant hairs called glandular trichomes, which are particularly abundant on female flower buds. Cannabinoid content and composition vary dramatically among Cannabis strains, with two general groupings distinguished: marijuana strains, […]

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Tracking the fate of Tetrodotoxin bound sodium channels

Pain is a global clinical problem. Chronic pain caused by cancer, osteo/rheumatoid arthritis, operations, injuries and spinal problems affects millions of people worldwide. The current treatments for severe pain is unsatisfactory and include opioids, non-steroidal anti-inflammatory drugs, corticosteroids and tricyclic anti-depressants. Most of these drugs have limitations with regard to addiction, toxicity and thus there is […]

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Web-based Goal Management Training™ in older adults with cognitive impairment: a randomized-controlled trial examining feasibility and efficacy

As the Canadian population is aging, more and more Canadians will show cognitive decline. Aging and certain types of neurological disorders is often associated with deficits in executive functions: goal maintenance, planning, task switching and attention. These functions are critical for the maintenance of functional independence. Few validated rehabilitation approaches for these types of deficits exist. One […]

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Using brain monitoring and video surveillance to reduce violent incidents in a care-facility environment

Increasingly prevalent patient violence within the dementia population is a challenge to long term care providers. Violent incidents can lead to serious musculoskeletal and neurological health complications. I propose to use video surveillance and a novel brain monitoring system in a care facility-based elderly population, to monitor violent episodes and brain vitality after incidents. This will […]

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Aerodynamic Noise of High-Lift Devices Year Two

The proposed project studies the noise sources of airplane high-lift devices (HLD) that are responsible for most of the aircraft noise at approach. The latter in turn creates noise nuisances that create health issues to populations close to large urban airports. Two approaches are followed. A state-of-the art simulation that predicts most of the turbulent […]

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Investigating the Implementation of Machine Learning Algorithms on Adiabatic Quantum Solvers

Machine learning is an active field of research and development to provide tools and technologies for finding significant patterns in data. Behind every face detection and face recognition software in digital cameras or social network websites a constantly under-development machine learning algorithm is working. Nowadays in any practical applications of machine learning we have to […]

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Exploring the potential synergistic cooperation between cellulase enzymes and lignin biocatalysts screened from a proprietary environmental DNA platform for deconstructing lignocellulosic biomass

MetaMixis, Inc., is a Canadain company undertaking a global effort dedicated to decreasing our reliance on petrochemicals by transitioning to engineered microbial processes or biocatalysts for the production of sustainable products. In the past few years MetaMixis has successfully developed a functional screen to recover metagenomic scaffolds sourced from various proprietary bacterial communities. They have […]

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Prototype of a CHP system based on an upgraded gravity-feed wood-pellet furnaceintegrated with a steam-powered micro turbine for small- to mid-scale applications using CFD simulation…

Biomass combustion is used to generate combined heat and power (CHP). The combustion furnace of this study (WiseWay) has been providing heat in small scales using wood pellets. The target of this project, however, is to upgrade the stove’s design (for larger scale purposes and other biomass types) and integrate it with a steam microturbine […]

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Energy Harvesting and Power Management Techniques for Hybrid-Powered Wearable Devices

igmotion Inc. was created to develop wearable health monitoring sensors and service the ‘at-home’ care segment of the elder care market. This project involves studying of existing literature and development of novel solutions for power management and energy harvesting for the product including tracking and fall detection systems using hybridpower. Analysis of proper control approaches […]

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Low cost and durable catalysts for automotive fuel cells

The successful commercialization of the automotive fuel cell requires lowering costs of key components in the fuel cell stack, such as the catalyst materials at the centre of the electrochemical cell generating the energy. Nanoparticles of platinum supported on mesoporous carbons are typical materials being used for the current generation of the fuel cell stack. […]

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Design of Multifunctional Nanoparticles for Nanomedicine Applications

Recently we have demonstrated that multicore-shell nanoparticles, made of cadmium telluride and zinc oxide, have great potential to be applied into the field of renewable energies due to the ability to split water into H+ and · OH upon irradiation of visible light. Herein we originally propose the utilization of those nanoparticles for a new […]

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