Toward an understanding of how YB-1 regulates drug resistance in glioblastoma multiforme through epigenetic regulation governed by BMI-1

Glioblastoma (GBM) is the most common and aggressive form of brain cancers and is the second most common cancer in children only behind leukemia. Conventional therapy consists primarily of surgery, radiation, and chemotherapy, and while these approaches have slightly improved the length of patient survival, there remains no cure for this disease. With the emerging […]

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Healing the body, healing the brain: Nutrition and exercise treatments for childhood neurodevelopmental disorders

In the absence of a clear set of recommendations from doctors for the treatment of neurodevelopmental disorders (NDD) such as fetal alcohol, cerebral palsy, and autism spectrum disorders, many parents and children affected by NDDs turn to unproven diet- and exercise-based treatments. While some research suggests that such interventions can boost brain functioning, very few […]

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A system dynamics model of the continuum of care for HIV

Operations Research — often referred to as the “Science of Better” — uses Mathematics to improve the efficiency of everything from the operation of airlines to hospitals. In collaboration with the BC Centre for Excellence in HIV/AIDS at St. Paul’s Hospital and Merck Frosst, this project will use Operations Research to improve the treatment and […]

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Online public consultation in the property development industry

Over the years, the methodology for public consultation has evolved to include public information meetings and hearings, telephone polls and surveys, and most recently online engagement. Increasingly, government is emphasizing evidence-based decision-making. They recognize that existing methods are lacking in reaching a broad demographic. Internet communication technology has made it possible to reach a broader […]

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Towards species specific management of invasive hawkweeds in British Columbia: Quantifying distributions, modeling potential invasion extent, and investigating genetic-morphometric congruence

The species of European hawkweeds present in British Columbia are aggressive and ecologically detrimental invaders of meadows, parks, agricultural lands and rangelands. Left unmanaged, these species could cost the province of British Columbia upwards of $60 million in economic losses by 2020. The Ministry of Forests, Lands and Natural Resource Operations (MoFLNRO) is responsible for […]

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Twitter Data Processing

Given the plurality of voices available on the Internet, it is often difficult to estimate the level of expertise of the individuals that one encounters in cyber-space. On the other hand, it is also difficult for any individual expert to establish their credibility in this sea of screaming voices. Therefore, it is desirable to have […]

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Victoria green economy

The proposed research is a collaboration between Vancity, the City of Victoria, and the University of Victoria to bring together the necessary information (financial, regulatory, and knowledge, respectively) to build a plan that will initiate Victoria’s Green Economy. Interns will be part of distinct interviewing panels that will research the needs, benefits, and obstacles of […]

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Investigation of adverse effects and healing factor properties of a novel formulation from Blue-O

The appearance of multidrug resistance of pathogens is challenging the researcher and industrial communities to develop more efficacious antimicrobial treatments. Blue-O Technology Incorporation (Blue-O Tech) has developed a novel formulation of medicine that accelerates the wound healing, while having an excellent antimicrobial strength over a broad spectrum of pathogens. The objectives of this study are to evaluate the cytotoxic effects, […]

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