The work proposed here is based on a novel and innovative approach which has not been addressed till today. We propose that developing a combined therapy to inhibit ErbBs and activate SSTRs, might be useful approach to control tumor progression and better hormonal therapy response in breast cancer. The outcome of the present study first, […]

The Dasiqox tribal Park, one of Canada’s most exciting current initiatives, was established in 2014 by the Tsilhqot’in First Nation following the Supreme Court of Canada’s landmark recognition of Tsilhqot’in Title in their territory. Dr. Bhattacharyya has been invited to work with Yunesit’in Development Enterprise, in collaboration with partnering First Nations and organizations, to develop […]

The Mount Polley tailings impoundment failure released 24 million m3 of mine-influenced water and sediment into the surrounding watershed. The scale of this spill is unprecedented in BC history, and the effects on current and future ecosystems are unknown. Of paramount concern is the containment of toxic metal-containing compounds that threaten aquatic life. My research […]

Research has shown that “no use” drug education programs, with the objective of scaring or shaming youth into abstinence, have not been effective in addressing problematic substance use. The ineffectiveness of such scare tactic approaches has led program developers to focus on prevention and harm reduction associated with drug use, or in general, health literacy […]

Pain in the craniofacial region is one of the more complex and difficult to treat conditions for patients and clinicians. Current treatments are complicated by limited efficacy and considerable side effects. Many of these conditions show greater prevalence in women than men, but there is a lack of basic research utilizing female animals. Recent advances […]

The aim of this project is to develop a wrist based fall detection and activity monitoring device for older adults. This device will be used to reliably and automatically detect falls and alert the health care providers so that immediate help can be dispatched and made available to fallers. In addition to detecting falls, this […]

The objective of this project is to develop lipid nanoparticle (LNP) reagents for the delivery of nucleic acids to turn off, or turn on target genes in “hard-to-transfect” neurons and stem cells in vitro and in vivo. A recent report (BCC Research, April 2011) observed that “51% of researchers employ cell-based techniques to perform transfection […]

This project recognizes the significant business challenges First Nations forestry enterprises face which have the effect of limiting the benefits to First Nations from forests (Wellstead and Stedman 2010). There is limited awareness of the conditions that affect the success and failure of Aboriginal enterprises in the forest sector (Trosper et al 2008). Research on […]

Yirun Ryan Li will be closely working with Dr. Shen, on his project that aims to observe, through empirical data, how IPO affects the Chinese market and how this effect is changing as IPO regulations evolve over time. Under Dr. Shen’s guidance, Ryan will study literature in the history of Chinese IPO regulations and identify […]

Changes in management and/or ownership at projects can cause regression in corporate-stakeholder relationships, as the changing faces and attitudes can lead to breakdowns in communication, misunderstandings, and conflict. Failure to maintain positive relationships with stakeholders can lead to significant costs for proponents, and is frequently cited as one of the most pressing issues facing the […]

Sikkim has preserved quite unique cultural artifacts of Tibetan Buddhism, and among those the most renowned is the thangka paintings. Through this project I would attempt to understand the cultural phenomenon of thangka paintings, how it has transformed in recent times. Thangka paintings portray the cosmology of Tibetan Buddhism, and it has captured the popular […]

The proposed research project is to develop a robust performance-based earthquake engineering (PBEE) methodology to quantify the seismic risks of large network of infrastructure such as the high-speed railway system in China. The project is anticipated to accomplish many goals. First, it will develop accurate numerical model to predict the seismic behavior of standard-span length […]