Improving glycerol utilization in E.coli for heme biosynthesis

Heme is a naturally occurring molecule found in our blood and as well as in animals, responsible for carrying oxygen throughout our body. Interestingly, heme has been commercially used in various products such as in cosmetics, nutraceuticals, and food. The traditional production of heme however often involves animal slaughter and harsh chemical processing, which is […]

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Saccade Concussion Diagnosis System

The underlying technology will leverage artificial intelligence (AI) to analyze oculomotor (eye movement) data to learn and extract human translatable features/symptoms of concussion. The software is computationally light-weight that is capable of running on portable hardware with minimal computational power. The intern will examine the system’s commercialization by conducting interviews with potential customers and identifying […]

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Silicone-mounted fiber-Bragg grating sensor for cardiac pulse-waveform monitoring

Cardiovascular disease (CVD) is a major cause of morbidity and mortality internationally. Current CVD diagnostics are limited to basic tools that provide a generalized number without quantitative indication of overall health, such as blood pressure, or lifestyle risk scores. More invasive diagnostic imaging can be done, but at great cost to the healthcare system. We […]

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Intraocular Pressure Monitoring Microfluidic Contact Lens

The proposed research project is to design a microfluidic contact lens that will be used to track the fluctuations in intraocular pressure. Intraocular pressure is the primary factor to monitor the progression of glaucoma, which is a chronic disease that leads to permanent vision loss and currently has no cure, making early and frequent testing […]

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Accelerated Maturation of Rye Spirits

Whisky is made by a process of fermentation, distillation, and maturation. The last step is by far the most time-consuming part of this process. In order for maturation to occur, the distilled spirit must sit in a wooden barrel for years, during which the spirit takes on the familiar colour and taste of whisky. This […]

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Novel Adhesive For Use In Sternal Fixation and Application

Median sternotomy is the standard approach in heart surgery. Over 1.5M operations are performed worldwide annually; 45K in Canada. Wires are used post-operatively to close the sterna, leading to instability, micro-motion and pain. Alternative techniques lack effectiveness or are cost prohibitive. Glass polyalkenoate cements (GPCs) are used in restorative dentistry, orthodontics and ear, nose and […]

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Nonlinear Section Model Tests in the Wind Tunnel for Cable-Supported Bridges

Due to the length and intrinsic flexibility of cable-supported bridges, wind causes serious challenges to designers of such structures. To ensure the safety of these bridges, it is common practice to test scale models of bridges in the wind tunnel. As bridges are getting longer, simplifications used for typical wind tunnel test become questionable. Therefore, […]

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Reliability Analysis of Gallium Nitride (GaN) Devices Using Data Analysis Methods

Gallium nitride (GaN) high-electron-mobility transistors (HEMTs) are good candidates to replace the traditional silicon-based transistors. Although these devices show superior performances compared to Si and SiC-based devices, they suffer from some reliability issues. The aim of this research project is to improve the performance of the GaN HEMTs and enhance their reliability by performing a […]

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Development of an Interoperable Microgrid Control Unit

The proposed project involves the development of a microgrid energy management system (or microgrid control unit – MCU) to synchronize the actions of devices such as batteries, solar panels, and other generators to achieve increased energy savings. The MCU will allow all devices to interact and exchange information seamlessly, in a “plug and play” fashion. […]

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Prevalence of moderate-to-severe Osteoarthritis pain of the hip and knee by Index Joints in Canadian Primary Care: A proof of concept study from the Canadian Primary Care Sentinel Surveillance Network

Osteoarthritis (OA) is a common disease in middle-aged and older Canadians attending primary care practitioners. As the Canadian population ages and with increasing obesity, OA will become an increasing burden for individuals and the health care system. Given the potential of Electronic Medical Record (EMR) data for surveillance of the population that is at high […]

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Exploring the Potential of Convalescent Plasma Therapy as an Intervention in the Pandemic Response

Convalescent plasma–used for over a century as the first treatment option in outbreaks caused by novel pathogens. The therapy involves transfusion of blood plasma from recovered donors, which contains antibodies, that can prevent or treat infection in recipients. Convalescent plasa therapy has been observed empirically or in small studies to confer passive immunity to susceptible […]

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