AAV Vectored Immunoprophylaxis for Prevention of Respiratory Infectious Diseases

This project aims to provide an alternative therapeutic for the prevention and treatment of the virus responsible for COVID-19, SARS-CoV-2, as well as respiratory syncytial virus and influenza. Using a single viral vector platform, we will deliver antibodies from human survivors of these diseases to provide sustained levels of protection against the virus for all […]

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Minimization of Switching Power Converter Ripples in RF Power Amplifier Circuits

As the power processing density in new technologies such as 5G and 6G increases, reduction of ripples caused by switching power converter operation becomes a gradually more difficult design problem to solve. Analysis of these ripples and exploring various methods for the ripple reduction in the RF power amplifier circuits are the main topics for […]

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Examining the ParticipACTION mobile app to promote physical activity among people who identify as women

Many Canadians currently do not meet government guidelines for weekly physical activity, particularly among people who identify as women. Media health (mHealth) such as fitness apps and tracking devices can help people to be more physically active. One such resource that has been developed for individuals living in Canada is the ParticipACTION mobile app. However, […]

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Development of a new bioassay for adiponectin agonist action

This project will pair together a academic Canadian research group with a pharmaceutical company who have developed a novel therapeutic (ALY688) to the stage that it will soon begin phase 1 clinical trials for the treatment of metabolic disease, such as diabetes. Since the success, and safety, of clinical trials requires accurate dosing of the […]

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Examining the feasibility and potential impact of a clinical innovative software tool to support pharmacists for minor ailment prescribing

Pharmacists are providing increasingly patient-centered clinical services such as Pharmacists Prescribing for Minor Ailments (PPMA). However, several factors delay pharmacists’ ability to implement PPMA including integration with workflow and time constrains. Technology solutions aim to support PPMA can be important innovative tools to help pharmacists to perform PPMA. The aim of this project is to […]

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A new automated approach for Engineering Design and Manufacturing Specification generation

RPS Composites Inc. designs and manufactures a wide range of corrosion-resistant (fibre reinforced plastic/polymer) FRP and Dual Laminate equipment from piping systems to ducts, stacks, hoods, covers, cells, and other miscellaneous custom equipment. Their engineering team has used different design methods provided in the codes and standards. The current process of designing and generating the […]

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Linear and non-linear replication factor models for Funds look-through

The Fundamental Review of the Trading Book (FRTB) is a set of regulations by the Basel committee, which is expected to be implemented by banks by 2022. The regulation targets market risk management in banking industry. The regulation targets market risk management in banking industry. According to FRTB, banks must decompose funds that can be […]

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Nurturing Good Beginnings: Evaluating and Assessing the YWCA’s community care program for new mothers/birthing parents

The YWCA aims to evaluate, through partnership with McMaster University, the impact of Good Beginnings, a program providing support for mothers/birthing parents who are vulnerable, precarious, and at-risk for postpartum depression. The program provides service for approximately 70 postpartum people and their babies annually, for a total of 500 people since 2014. During these six […]

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Investigating the role of bacteria in abdominal pain and chronic constipation.

The bacteria living in our gastrointestinal system, the gut microbiome, play a key role in human health and disease. Multiple studies demonstrated altered gut microbiome in patients with constipation or abdominal pain but knowledge of a clear cause-effect relationship or underlying mechanism are lacking. We found previously that microbiota from patients with irritable bowel syndrome […]

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Joint Force System Research & Development

The purpose of this project is to design and evaluate a biofeedback device to help users to complete isometric shoulder and knee joint exercises. Specifically, the device, currently called the “Joint Force System (JFS)”, will measure the user’s force output and exercise form, and provide feedback to encourage ideal levels of effort and correct postures […]

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Synthesis and characterization of various nanocarriers and ministring DNA product for ocular gene delivery

Gene therapy has the potential to effectively treat a wide range of ocular disorders. However, the introduction of foreign therapeutic genes to cells is incredibly challenging. Compared to viral vectors, non-viral vectors (NVV) are far less immunogenic and less toxic. However, NVV are less efficient than viral vectors at delivering therapeutic genes because they must […]

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