A New Decision-Support Tool for the Treatment of Patients Suffering from a Torn Anterior Cruciate Ligament

After a ligament injury to the knee, clinicians must decide on an optimal treatment for their patient. In most cases, they prescribe either conservative therapies (physiotherapy with or without orthotics) or surgery (which allows doctors to use two different grafts). The Centre du genou Emovi proposes a biomechanical assessment to better understand the functional status […]

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Antibody Modeling Using a Combined Computational/Experimental Protocol

The proposed project combines structural biochemistry with high-performance molecular simulations to generate valuable insight into the development of the next generation of ligands that can be used to develop vaccines. The collaboration between the academic and industry partner creates an ideal opportunity to combine theoretical and experimental approaches for better lead generation and development of […]

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Computational/Experimental Protocol for Development of a Therapeutic Agent for Treatment of Tuberculosis

It is estimated that one third of the world’s population is infected by Mycobacterium tuberculosis. With the emergence of drug resistant tuberculosis, the World Health Organization has declared tuberculosis a global health emergency. UDP-galactopyranose mutase, an enzyme essential for tuberculosis bacterial growth and infection, will be studied by a protocol which combines advanced NMR and […]

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The Identification of Gene-Environment Interactions in Non-Hodgkins Lymphoma

Non-Hodgkins Lymphoma (NHL)is the 5th most common cancer in Canada and its incidence has been increasing steadily every year. Unfortunately, little is known about the causes of the increased incidence, although it is likely that some combinations of genetic and environmental factors are involved. This internship with the BC Cancer Agency will examine genes that […]

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Development of Oral Appliance Technology for the Treatment of Sleep Disordered Breathing in Children

The overall objective of this pilot study is to develop design, manufacturing and clinical protocols for the application of Klearway’s oral appliance therapy to a child population. By evaluating orthodontic records (questionnaires, x-rays and dental study models) together with blood oxygen levels before and after treatment, new applications for Klearway’s oral appliance use and new […]

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Examining the Relationship Between Subjective Experience and Outcomes in Individuals with Mental Illness and Substance Abuse

The proposed research project will assess psychiatric patients shortly before hospital discharge and then conduct follow-up assessments once a month in the community for three months. Assessment will include data collected from interviews as well as file reviews and will focus on the effect of patient perceptions on therapeutic and adverse outcomes. Specifically, the intern […]

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Evaluation of a Regionalized Approach Toward Providing Emergency Medical Services in British Columbia: Is Distance to Services a Critical Factor in Injury Mortality?

One of the primary reasons for this regionalization of health care in British Columbia is so that more resources can be spent on direct patient care and less on bureaucracy and duplication. A critical component of this systems approach is equipping selected facilities with the resources to treat the most severely injured patients. Distance to […]

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Angle optimization of intensity modulated radiation therapy via learning algorithms

The internship describes a novel method for improvement of Intensity Modulated Radiation Therapy for cancer treatment. The intern’s team will implement a learning algorithm approach to design the number and value of orientations of the gantry that will optimize the radiation dose to the planned target volume while at the same time minimizing dose and […]

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But I Thought I had Asthma – Now What? Assessing the Feasibility of a Treatment Program for Patients with Functional Dyspnea

The medical team at the Asthma Centre at St. Joseph’s Hospital in London, Ontario is dedicated to providing the best care for its patients. Extensive investigations at the clinic have revealed that many patients present with functional dyspnea, the experience of breathlessness without an identifiable cause. Despite its undetectable organic pathology, those affected by functional […]

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A Wireless Wearable Multi-parameter Physiology Multi-sensor System

Miniaturization and microintegration is well known for their potentials in providing microsystems and sensors with unmatched performance, reliability, and lower costs. Current technologies in implementation of microsensors, however, span a large variety of platforms. It is thus common for microsensors measuring differing parameters to exist on different combinations of substrates, not to even mention the […]

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