Techna Guided Therapeutics Cluster

The Guided Therapeutics (GTx) Core of the Techna Institute is developing innovative imaging technology and therapeutic approaches, and translating those advances to commercial and clinical applications. Working with our industrial partners Precision X-Ray and Elekta, the Mitacs-supported interns will develop new capabilities and tools for preclinical image-guided radiation therapy devices and radiosurgical techniques. With Precision […]

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Evolving a system for effective communication with non-speaking patients in emergencies

Individuals with cerebral palsy generally use augmentative and alternative communication (AAC) devices to help them interact socially. The vocabularies provided in these systems are not specifically helpful in communicating during medical emergency or hospital intensive care. This project involves user-centered design and development of a software module for use in such situations, based on a […]

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Statistical Analysis of Prostate Brachytherapy Treatment Data

Using data obtained over a period of 15 years from Brachytherapy procedures used on patients to treat prostate cancer, statistical analysis will be carried out to confirm the hypothesis that Brachtherapy treatments offer the best outcomes at the lowest cost incomparison to other treatment modalities. The first stage of the project will be to review […]

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Development of an image-guided navigation platform for an automated and MRI-compatible robotic needle guiding device for percutaneous procedures

Prostate cancer is the second most cancer related death in men, accounting for over 111 M$ yearly in Canada. Current prostate biopsy or therapy procedures such as transperineal brachytherapy use transrectal ultrasound guidance and  a  template to guide needles along parallel trajectories. However, pubic arch interference (PAI) with the implant path obstructs part of the […]

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Data Anonymization for Medical Records

Data anonymization focuses on removing any personal or other information that would identify an individual or a set of persons from a given collection of records. In addition, anonymization should also mask information that could potentially be combined with other publicly available data to reidentify the individuals. This project aims to study data anonymization for […]

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Development of innovative solutions for analyzing biological samples in pharmaceutical research and development: Novel bioanalytical chemistry merges digital microfluidics and mass spectrometry

Diagnostic tests that currently direct patient therapy in cancer and other diseases are more typically performed at the genetic level, despite the fact that the beneficial response to drugs and the development of resistance are rooted in the proteins that comprise the cell’s signaling pathways. We argue that this is a major gap, as proteomics […]

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Local in situ Controlled Delivery of Biphosphonates in Bone Metastasis

We propose to develop in collaboration with Medtronic Canada a bioceramic drug delivery system for the local controlled release of Biphosphonates (BP) – drugs that prevent bone resorption – to promote both tumor inhibition and bone regeneration at the site of bone tumor resection, eliminating the need for high systemic doses and side effects associated […]

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Cancer detection and Muscle

Cancer is a highly prevalent disease. Rapid and early detection is very important for the health of individuals. In this proposal we will employ a specialized technique developed by Panacea Global to detect the onset of cancer in both animal and cancerous muscle cells, and uniquely investigate the role of exercise in cancer progression.

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The role of remote ischemic preconditioning (RIPC) in preventing organ dysfunction following hemorrhagic shock: a translational study

Dysfunction of vital organs is one major reason why trauma victims die after sustaining a major injury, even though the organs themselves may not have been directly injured. One intervention proposed to prevent development of distant organ injury is called “Remote Ischemic Preconditioning” (RIPC), wherein application of intermittent occlusion and release of blood flow to […]

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Automatic Segmentation of SCG Signal for Ischemic Patients

Research has shown that by monitoring the vibration of the heart using a simple sensor mounting on the human chest, the mechanical characteristics of heart can be measured. The purpose of this research is to design software that can automatically find some important points on the SCG signal. The software will be used to find […]

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