The “CARE” (Clinical Analytics for Real-World Evidence) Platform

The healthcare industry is shifting from randomized controlled trials (RCTs) care to real world data (RWD) to understand how well an intervention performs in clinical practice. The best source of RWD is source data – that is, data that are collected at the interface of the patient and the health care system. The University of […]

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EARtrode, a wireless in-ear custom-fitted intelligent brain computer interface – Year 2

Brain-computer interfaces (BCI) can directly translate human intentions into discrete commands, bypassing the motor system. Most non-invasive BCI systems currently in use are based on electroencephalography (EEG) recording technology. While traditional EEG-based BCIs achieve high information transfer rates, these systems have two major limitations. First, they cannot be used in daily life as they do […]

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Evaluation Capacity Network: Aligning Evaluative Thinking and Practice among Early Childhood Stakeholders

This project aims to provide evidence and research support to BGCBigs in the implementation of their Building an Evaluation Framework and Capacity for Sustainability project. BGCBigs recognizes that achieving their goal of ‘supporting our children and youth on the path to success’ depends upon an organization committed to evaluative thinking, learning and utilization of evidence […]

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Developing a microfluidic lung-on-a-chip model for accelerating the discovery of novel therapeutic targets for Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. There is a pressing need to discover novel targets to enable precision health, promote new therapeutic discoveries, and […]

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From the ParticipACTION Physical Activity Report Card to the Global Matrix 3.0: Impact Evaluation and Strategy Development

Internationally, physical activity levels among children and youth are declining, while sedentary behaviours are increasing, leading to the global rise in non-communicable disease. This project aims to contribute to childhood physical activity promotion in Canada and worldwide, and to the international diffusion of scientific knowledge concerning childhood physical activity though three actions: 1. the evaluation […]

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Salivary insulin profiles throughout the day in healthy humans

The hormone insulin rises in the blood after consuming food. Too high of an insulin response may be a sign of dysfunctional metabolism and has also been shown to promote weight gain. Thus, if insulin levels rise too high after a meal it may indicate that someone is metabolically unhealthy or is prone to obesity. […]

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HAT TRICK: An innovative health promotion program for men

Despite the benefits associated with staying physically active and eating a healthy diet, men are less likely than women to engage in these behaviours. Healthy lifestyle programs that are offered in collaboration with professional sport teams have been found to engage men in being more active and eating healthier. HAT TRICK was designed to specifically target […]

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Development of a High Power Picosecond Infrared Laser for Medical Applications

This project will focus on furthering the development of a compact picosecond infrared laser (PIRL) system for use in surgical applications. This laser system, which represents a new paradigm for laser surgery, is unique in its ability to provide high-speed cutting of biological tissue without the collateral damage to surrounding tissues inherent in current surgical […]

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Developing a new magnetic sensor for application in biosensing and surveying – Year 2

Detecting subtle chemical and physical changes occurring at the early stages of chronic disease and many other infectious diseases caused by harmful bacteria is still a challenge, as ultra-sensitive sensors with large signal-to-noise-ratio are required to detect them. We recently explored new ways to enhance the sensitivity of magnetic nano-sensors and theoretically demonstrated that under […]

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Development and Validation of Software for the Three-dimensional Quantification and Visualization of Blood Flow Hemodynamics in Patients with Aortic Insufficiency using 4D flow MRI. Year 2

The aim of this proposal is to assist in the development and validation of a dedicated 4D flow MRI analysis software for the evaluation of aortic valve insufficiency. Before being commercialized this software requires validation considering the large amount of data required to be pre-processed (over 2,000 files per case), elemental data corrections, data analysis […]

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Performance analytics and monitoring in ice-hockey

In professional sports, sustained performance largely depends on having the best players healthy and free of injury. Player testing and monitoring has become a key area of development for many professional teams in order to track players’ health and performance. The purpose of this project is to build on the partner organization’s player monitoring program […]

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