Development of Cerebral Perfusion Technology

Medtronic is a global medical device company and leader in patient monitoring technologies that has a key area of interest for developing technology to effectively monitor patients’ cerebral blood flow (i.e., perfusion) in relation to systemic blood pressure. Maintaining a prescribed intra-operative blood pressure range for patients does not guarantee a healthy cerebral blood flow, […]

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Statistical and Physiological Beat Modelling of Seismocardiogram Signal – Year 2

“Seismocardiogram (SCG) is a signal that is captured by placing an accelerometer on the human chest. This signal captures very important timing information such as opening and closing of the heart valves. In addition to these timing information, the non-invasive nature of this signal makes it an attractive solution for remote monitoring of patients with […]

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Functional Proteomics to Inform Targeted Therapy for Head and Neck Cancer

To ensure effective cancer treatment, it is vital to match the drug with the molecular characteristics of the patient’s tumor. This research project is focused on developing functional diagnostic assays that may be used eventually in the clinic to stratify patients for targeted therapies. The project will provide a unique opportunity for the interns to […]

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Do Physical Activity Levels Predict Functional Improvements following a Structured Exercise Program for Women Undergoing Breast Cancer Treatment?

Breast cancer is the most commonly diagnosed cancer in Canadian women, representing 26 percent of all diagnostics. The overall cancer survival rate has increased from 25% in the 1940s to 60%. Thus, the proportion of breast cancer survivors is increasing significantly. There is a consensus that survivors benefit from exercise during and after treatment. However, […]

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BoneTape: A Novel Craniomaxillofacial Fixation Technology

Craniofacial fractures require stabilization to restore appearance, facilitate healing and improve patient’s outcomes. The current standard of care is rigid titanium plates, which require drilling, screws and bending of titanium plates with plyers during surgery to conform to the complex geometry of the face. This is an over engineered solution that is not only difficult […]

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The development of a novel oncolytic virotherapy for acute myeloid leukemia

Modern molecularly targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute blood cancer patients. This is largely due to the survival of some blood cancer cells that possess unique properties and can cause treatment failure or relapse, highlighting the need for new therapies. In collaboration with […]

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Implementation and advancement of image analysis for multiplexed microarrays

Microarray testing allows high-volume analysis. This work will compare open-source software to in-house analysis methods within SQI Diagnostics. The goal is to enhance the performance of current assay designs and to inform and guide the next-generation of assay designs (ie 384 well plates) which will support SQI’s technology leadership position. After implementing a print run […]

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A modular re-configurable robot for real time MR image guided applications

Minimally invasive techniques are used for a wide variety of procedures in the diagnosis and treatment of cancer. Many procedures require insertion of a needle along a straight-line path to the site of the disease. Real-time magnetic resonance (MR) imaging offers the means to visualize the needle relative to a small target lesion and avoid […]

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Blockchain-based Consent Management for Personalized Medicine

This multidisciplinary project will investigate the social, data, and technical issues surrounding design and implementation of a blockchain-based solution for the management of consent for the use of individuals’ “omics” data in medical research. Blockchains are distributed ledgers in which confirmed and validated blocks are organized in an append-only chain using cryptographic links. This project […]

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