Technology innovations in Wheelchair Sport measurement and analysis

This project will assess the game demands of wheelchair court sports. While this has been attempted in the past, new methods using inertial measurement units (IMU) allow each push to be identified and offer new ways to analyze these game demands and connect them to key performance metrics. With the help of Own the Podium, […]

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A Novel Bone Anabolic Treatment in a Mouse Model of Osteogenesis Imperfecta

Osteogenesis imperfecta (OI) is a heritable disorder that causes bone fractures. The drugs that are used at present help to decrease the number of fractures by about half, but most people with OI have many fractures despite receiving currently available treatments. Mesentech Inc has developed a new drug that has shown a strong effect on […]

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Radiofrequency Treatment for Emphysema in Mouse Model

Emphysema, a lung disease that millions of Canadians currently suffer from, has few safe and non-invasive options available. One of the features of emphysema is the lack of proper blood flow in the diseased lungs and this results in poor gas exchange. IKOMED Technologies Inc. has been developing a new technology that has the potential […]

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Efficacy of CB1R inverse agonists for enhancing insulin secretion in mouse and human islets, ex vivo, and for preventing cytokine-induced ?-cell death in human islets

Inversago and CR-CHUM will collaborate to evaluate new generation Cannabinoid-1 receptor (CB1) blockers for the treatment and/or prevention of type-1 and type-2 diabetes. Previous generations of CB1 blockers have shown their promise in treating several features of the metabolic syndrome, including obesity, type-2 diabetes and liver diseases. However, they were plagued with important psychiatric adverse […]

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Testing of a Collar-Mounted Airbag to Protect Against Neck Injuries and Concussions

Hockey parents are worried about rising concussion rates. Currently no sports equipment protects against concussions. Hockey players aged under 18, must wear a neck guard for protection against skate blade cuts. Recently, a redesigned hockey neck guard, using an impact sensor and airbag technology was conceptualized. We want to test whether airbag inflation upon direct […]

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Machine learning methods for automatic diagnosis, severity assessment, prognosis, and disease understanding of COPD

Chronic Obstructive Pulmonary Disease (COPD) is a progressive, debilitating, chronic respiratory disease that affects 600 million people worldwide and is responsible for 3 million deaths worldwide each year. Given the recent advances in artificial intelligence (AI) and the availability of large datasets from both the public and private sectors, our project applies AI to analyze […]

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Calibration-Free Continuous Pulse Oximeter Monitoring Using Deep Learning

Oxygen saturation, i.e. SpO2 is the fifth most important vital sign after heart rate (HR), body temperature (BT), blood pressure (BP), and breathing rate (BR). Oxygen saturation indicates if sufficient oxygen is being supplied to the body. Continuous SpO2 monitoring is highly beneficial for detection and prevention of several diseases. In more details, continuous SpO2 […]

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Effect of ROS on neurovascular decoupling in epilepsy

In order for the brain to function well, it is important that blood vessels within the brain are healthy. In a healthy brain, these blood vessels can become larger and smaller when necessary, but this is no longer possible after epileptic seizures. An important group of compounds that regulate the size of blood vessels is […]

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Evaluation of MRI-based estimation of cortical thickness

The most important structure in the human brain is the cerebral cortex. It makes it possible to perceive our visual environment and sounds, to perform motoric actions such as grasping an object, to speak, to understand speech, etc. The cerebral cortex is a 2-5 mm thick sheet, embedded in the skull. Analysis of MRI data […]

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