In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem […]

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Evaluation of the CACE Homecare Curriculum

In January 2016, the Centre for Ambulatory Care Education (CACE) at Women’s College Hospital completed the Homecare Curriculum. This online, simulation-based program is designed to help personal support workers, nurses, and rehabilitation professionals provide better care for older adults who wish to stay in their homes. The program presents learners with 3 virtual home environments […]

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KINARM Standard Tests’ Task Scores: towards a validated and effective tool for communicating to clinical communities KINARM measures of brain function

KINARM Labs™ provide robust and objective measures of brain function and dysfunction by the precise measurement of human behavior with robotics. Created by neuroscientists, KINARM Labs allow clinician-scientists to detect and quantify the sensory, motor and cognitive impact of a diverse range neurological impairments caused by stroke, cardiac arrest, TIA, mTBI, concussion, MS or Parkinson’s […]

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Pressure Ulcer Biobank from Spinal Cord Injury Patients

Pressure ulcers (PUs) are a major health problem in people with spinal cord injuries (SCIs). PUs increase hospital admissions, with 25% of SCI treatment cost linked to PU management. Currently, treatment is limited and new therapeutic options are required. Wound fluid from PUs is invaluable for researchers as it allows a detailed study of the […]

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Pilot Study of the Safety and Efficacy of Different Potencies of Vaporized Marijuana Participants with Chronic, Treatment-Resistant Posttraumatic Stress Disorder (PTSD)

This study is among the first studies examining the effects of whole plant herbal cannabis on a variety of outcomes, including mental health conditions, anxiety, mood, and sleep quality. The interns will gain valuable experience in the field of medical cannabis, and will collect important data on the effects of varying strains of cannabis on […]

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Budget impact analysis of Rapid Endovascular Treatment of Ischemic Stroke

The return on investment for medical imaging, interventional radiology, is not well understood, with limited existing research on the value realised from the funds spent. It is expected that the Hot Stroke Intervention by interventional radiologists will not only add direct value to the health care system but will have far reaching and significant impact […]

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iMALDI-based Assays for Protein Activity to Improve Patient Selection for Therapeutic Akt Inhibitors in Cancer Treatment

Detailed profiling with modern analytical technologies has shown that most cancer types are composed of multiple small sub-populations with distinct molecular signatures. Correct identification of the cancer subtype can predict its response to a particular treatment. Genomics has commonly been applied for this purpose, but in some cases, our ability to predict drug response may […]

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Investigation and development of plasma-based cancer diagnostic

The blood of cancer patients contains DNA that has been shed by their tumours (circulating tumour DNA or ctDNA). As such, any genetic mutations in the tumour may be detected in the patient’s blood. Theoretically, patients can be followed and monitored through analysis of ctDNA, which would reveal if the patient is responding to treatment, […]

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