Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

29670 Completed Projects

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Projects by Category

Metal Organic Frameworks (MOFs) as hypergolic additives for rocket propulsion

The space industry is growing ever larger, with many commercial solutions being actively developed. Hybrid rocket engines fulfill a need in smaller launchers, to launch small satellites. These satellites currently have to wait in queue, often for several years, in order to obtain a place on the big launchers currently available. Solutions developed locally by startup companies would enable more frequent launches of smaller payloads. A key technology that permits this is hybrid rocket engines, with lesser complexity than liquid engines, and greater performance than solid rocket boosters.
Novel fuel mixtures are currently being investigated, as greener alternatives than what is commonly used (hydrazine derivatives). Hypergolic fuels ignite spontaneously on contact with the oxidizer, and therefore further reduce engine complexity by removing the need for an ignition system. Metal Organic Frameworks (MOFs) have shown such hypergolic properties. The objective of this project is to investigate these novel hypergolic fuels and ultimately assess their viability in engine conditions.
The research done in this project will increase our understanding of Metal Organic Frameworks (MOFs) and their interaction with common oxidizers, such as white fuming nitric acid (WFNA), and green alternatives, such as hydrogen peroxide.

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Faculty Supervisor:

Etienne Robert

Student:

Partner:

ACSYNAM

Discipline:

Engineering

Sector:

Manufacturing

University:

Polytechnique Montréal

Program:

Accelerate

Derivation of biased bitopic ligands for class A GPCRs – an NMR approach

Our goal is to employ a host of new compounds, made by the applicant in her lab in Brazil, for drug discovery studies at the University of Toronto. Specifically, the host uses a technique called Nuclear Magnetic Resonance (NMR) to obtain signatures of drugs or ligands. These signatures can identify those compounds which bind strongly to the drug target – in this case a membrane protein belonging to an important family of membrane proteins call G Protein-Coupled Receptors (GPCRs). 30-40% of all drugs actually target GPCRs making this an important class of drug targets. The NMR used by the host PI focuses on compounds or species which are fluorinated. The associated 19F (fluorine) NMR is probably more sensitive than any other NMR approach in terms of identifying binding species. The student will perform docking experiments, learn how to implement the fragment based drug discovery methods using NMR, learn how to express and purify the membrane receptors, and test her new compounds for compatibility with the existing library and potential to modulate receptor action (ie serve as drugs).

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Faculty Supervisor:

Scott Prosser

Student:

Partner:

Universidade Estadual de Maringá

Discipline:

Life Sciences

Sector:

Pharmaceuticals; Biotechnology; Health and Related Sciences & Technology

University:

University of Toronto

Program:

Globalink Research Award

Développement d’un cadre d’analyse des données collectées par les organismes des arts de la scène pendant la période de COVID-19

La crise de la COVID-19 a stimulé le besoin de transformation numérique des organisations afin d’adapter leurs modèles et pratiques d’af-faires pour survivre à la pandémie. Compte tenu de la nature de la consommation directe de la plupart des offres culturelles, le secteur cultu-rel semble souffrir de la pandémie de COVID-19 plus que les autres industries. Dans cette perspective, notre projet de recherche vise à proposer une approche pour la conception et la mise en œuvre d’un cadre d’analyse des données collectées sur les publics par les organismes des arts de la scène pendant la COVID-19 en mettant l’accent sur des outils qui soutiennent la visualisation et les décisions basées sur les données. Ces outils seront développés à partir d’une analyse des différentes périodes de fermeture, ouverture et autres conditions qui ont été imposées par le gouvernement du Québec aux salles de spectacle combinées à des sources de données fournies par des partenaires de Sy-napse C qui serviront de cas d’usage.

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Faculty Supervisor:

Thomas Hurtut

Student:

Partner:

Synapse C

Discipline:

Computer science

Sector:

Information and cultural industries; Professional, scientific and technical services

University:

Polytechnique Montréal

Program:

Accelerate

Improving Measurement for Near Term Quantum Computers

The ability to simulate chemistry accurately allows for significant developments in many fields such as material and drug
discovery. Unfortunately, the underlying equations that describe chemistry become exponentially harder to solve as we increase
the size of the system. This makes it impossible for us to accurately simulate useful molecules on classical computers. A potential
solution to this is quantum computing. In the near term, an algorithm called the Variational Quantum Eigensolver could be used
on quantum computers for the problem. However, one of the limiting factors of this algorithm is the time taken to measure
quantities, such as energy of a molecule, from the quantum computer. The project aims to find techniques to reduce the number
and therefore time needed to accurately measure quantities, and hence improve the speed of quantum computers. We intend to
do this through the idea of ghost Paulis. These are additional ‘operators’ that we add to what we measure, that don’t change the
value measured but reduce the number of measurements we need to accurately determine the value.

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Faculty Supervisor:

Artur Izmaylov

Student:

Partner:

University of Oxford

Discipline:

Physics

Sector:

Quantum Science

University:

University of Toronto

Program:

Globalink Research Award

Social Determinants and Quality of Life Measurement Framework for Indigenous Digital Health Systems

This research project will involve exploration, analysis and consultation for developing of a framework integrating information about social determinants of health and quality of life measures into an Indigenous Digital Health Ecosystem. The framework will include guidance for collecting, analyzing, and using social and health data to inform policy, investment, clinical, and service actions in First Nations communities. The research will leverage the work of the World Health Organization (WHO) on integrated people-centred health services and will be guided by indigenous perspectives and participatory engagement with First Nations communities and stakeholders. In so doing, the research will provide the evidence required for the partner organizations to collaborative develop a new culturally aligned digital platform(“MIS Platform”) and a suite of integrated applications that meet the unique needs of the target indigenous communities to support social determinants of health, ownership and control of data, and Nation-building.

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Faculty Supervisor:

Rick Sawatzky

Student:

Partner:

Mustimuhw Information Solutions Inc.

Discipline:

Life Sciences

Sector:

Information and cultural industries

University:

Trinity Western University

Program:

Accelerate

Beyond accuracy: robustness and generalization properties of biologically plausible learning rules

The overarching goal of my research is to investigate how the brain learns in order to develop brain-inspired learning algorithms that will reduce the computational cost for many machine learning applications. The standard learning algorithm (or learning rule) for training artificial neural networks (ANNs) can be extremely costly in terms of computation and storage, driving a search for more efficient learning algorithms. Meanwhile, the brain excels at learning patterns across multiple timescales efficiently, thereby motivating an influx of biologically motivated learning algorithms. However, the robustness and generalization properties of these learning rules are severely underexamined. Here, we aim to investigate and improve the generalization capabilities of biologically plausible learning algorithms by leveraging recent experimental neuroscience findings as well as theoretical tools from deep learning.

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Faculty Supervisor:

Guillaume Lajoie

Student:

Partner:

University of Washington

Discipline:

Computer science

Sector:

Education

University:

Université de Montréal

Program:

Globalink Research Award

Effects of a parent intervention with a growth mindset approach on the quality of parent-child interaction

The quality of parent-child interactions is among the most important active ingredients of early language development. Many interventions, which vary in approach, content and format, focus on improving the quality of these interactions between children and their caregivers in order to promote early language development. Understanding the relationship between the characteristics of these interventions and their effects on parent-child interactions is crucial to developing effective intervention methods. The purpose of this research project is to document the effects of an intervention aimed at providing information to parents about language development using a growth mindset (i.e., sharing the idea that children’s language development is malleable and that parents can help their children’s language grow by conducting specific actions), on the quality of parent-child interaction. The results of this study have the potential to provide practitioners working with young children and their families with evidence-based knowledge to better support parents in fostering their child’s early language development.

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Faculty Supervisor:

Louise Potvin

Student:

Partner:

Harvard University

Discipline:

Sociology

Sector:

Education

University:

Université de Montréal

Program:

Globalink Research Award

L’évolution de l’identité francophone en Bulgarie depuis 1993

Depuis son institutionnalisation en 1970, la Francophonie n’a eu de cesse de faire évoluer ses caractéristiques identitaires. Elle est ainsi passée de centrer sur la France à une multitude de centres au sein de l’ensemble des pays francophones, et de culturelle à politique et diplomatique.
Le projet de recherche s’attache alors à identifier, à travers d’entrevues semi-dirigées et une analyse du matériel scolaire bulgare, si l’évolution connue de la Francophonie s’est effectuée au sein des représentations de la francophonie en Bulgarie, et les raisons de cette évolution supposée. Effectivement, la Bulgarie a choisi la langue française en tant que langue étrangère d’excellence, et entretenait avant 1993 une relation privilégiée avec la France. Depuis son adhésion à l’OIF en 1993, il s’agira alors de savoir si cette représentation de la langue française, de la francophonie en Bulgarie n’est encore perçue qu’au travers de cette exclusivité franco-bulgare.
Les résultats de ce projet de recherche tentera ainsi d’établir un parallèle, effectif ou non, entre l’évolution de l’identité collective de la francophonie en Bulgarie et l’évolution de l’identité collective de la Francophonie.

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Faculty Supervisor:

Magdalena Dembinska

Student:

Partner:

Sofia University

Discipline:

Sociology

Sector:

Public Service, Policy, and Governance; Education

University:

Université de Montréal

Program:

Globalink Research Award

Identifying putative antibiotic resistance genes (ARGs) in the ancient oral cavity from the Industrial Revolution

This project plans to use dental calculus (miniralised plaque) samples to acquire a better understanding of the development of antimicrobial resistance (AMR) in the human oral microbiome. This will be the first metagenomic study regarding antibiotic resistance genes dating back to the Industrial Revolution (c. 1750-1850). We expect to detect some evidence of ARGs based on the notion that ARGs are an intrinsic element of the oral microbiome. However, it is anticipated that predecessors of today’s antibiotic-resistant bacteria will lack the same ARGs, since the antibiotic era (c. 1940) is likely to have pushed this gene acquisition. Bioinformatic techniques, such as phylogenetic reconstruction, of these bacteria aims to give further insight on when, where, and at what rate these ARGs were obtained from the Industrial Revolution to the antibiotic (modern) era. The project will entail writing a report that includes a literature review, a section on wet laboratory and bioinformatics methodology, and final outcomes. These findings will be used to inform the final data analysis for our PhD dissertations, which will be co-prepared for peer-review publication.

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Faculty Supervisor:

Camilla Filomena Speller

Student:

Partner:

University of Bradford

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Other

University:

The University of British Columbia

Program:

Globalink Research Award

Muscle stem cell-niche interactions predicted in silico

Skeletal muscle, an essential organ system making up 30-40% of total body mass, is unique in that it allows for the body’s
voluntary movement. It is solicited and stressed daily and consequently possesses the remarkable ability to regenerate in
response to injury due to a special population of cells named muscle stem cells (MuSCS). At rest, MuSCs are found in a sleep
state called quiescence, which has been notoriously challenging to study due to the high risk of waking i.e., activating them with
current techniques. Our group thus developed a cell culture system that can induce this sleep state in MuSCs in a laboratory
setting. With this as a tool, our goal now is to identify, and then test, computer predicted communications between MuSCs and
other cell types during this sleep state to better understand which signals regulate it and how they become dysfunctional in cases
of diseases such as aging.

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Faculty Supervisor:

Penney Gilbert

Student:

Partner:

Université de Lyon (Lyon, France)

Discipline:

Life Sciences

Sector:

Biotechnology; Health and Related Sciences & Technology

University:

University of Toronto

Program:

Globalink Research Award

Molecular genetic analysis of a novel class of negative regulators of cell proliferation

My research focuses on understanding the mechanism of action of a new class of tumor suppressor genes using the well
established round worm (nematode) model system. Previously published data from Gupta and Chamberlin lab have shown that
deleting the function of these genes causes excessive proliferation of cells (similar to cancerous growth). To further understand
their role, I have carried out several experiments in Gupta lab. My next set of experiments involve generating transgenic strains
for which I will be visiting Dr. Chamberlin’s lab. My results will reveal the mechanistic roles of these genes which will be beneficial
in understanding how their homologs function in restricting cell proliferation in higher eukaryotes. Ultimately, the findings of my
research will lead to a better understanding of genetic mechanisms underlying cancerous growth thereby facilitating in the
development of targeted therapeutics against cancers.

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Faculty Supervisor:

Bhagwati Gupta

Student:

Partner:

Ohio State University

Discipline:

Life Sciences

Sector:

Biotechnology; Life Sciences (not health)

University:

McMaster University

Program:

Globalink Research Award

Hover Business Strategy Internship

Hover is looking to hire interns to help with the testing and development of Drone Delivery in Canada. The Canadian technology industry typically lags behind the United States, and so in addition to helping with the MVP of drone delivery testing to see demand, we also are aiming to help move the Canadian ecosystem forward and help innovate within our cities. The intern would be helping to develop partnerships with businesses interested in this technology, while analyzing and strategizing the Drone Delivery MVP. Hover will benefit from the help & information received and since we are a small company, the interns will have the chance to help make decisions that will directly impact the future of the company.

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Faculty Supervisor:

Diego Coraiola

Student:

Partner:

Hover

Discipline:

Business

Sector:

Manufacturing; Professional, scientific and technical services; Transportation and warehousing

University:

University of Victoria

Program:

Business Strategy Internship

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