Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

13270 Completed Projects

1072
AB
2795
BC
430
MB
106
NF
348
SK
4184
ON
2671
QC
43
PE
209
NB
474
NS

Projects by Category

10%
Computer science
9%
Engineering
1%
Engineering - biomedical
4%
Engineering - chemical / biological

Synthesis and evaluation of Antibody conjugated to cyclical peptide toxin drug for the treatment of multi-drug resistant cancer cells

Antibody Drug Conjugates (ADC) are an emerging class of drugs that combine antibodies and a drug payload. The antibody cargoes the drug payload to specific targeted cells improving both safety and efficacy. To date that are 8 FDA approved ADC drugs all for oncology application using small molecule drugs. Although these ADCs with small molecules encompass superior efficacy and safety than non-targeted small molecule drugs, it is increasingly evident that they lose efficacy due to the same multi-drug resistance by the cancer cells. In this project, we are exploring the synthesis and evaluation of larger molecule cyclical peptide toxin drugs that cancer cells find more challenging to develop resistance to. Traditionally, these cyclical peptide toxins are rarely used for oncology application due to a variety of systemic toxicity; however, by utilizing the ADC platform, this new class of toxins may be an important class of anti-cancer drug class to unlock.

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Faculty Supervisor:

David Perin

Student:

Benjamin Noichl

Partner:

iProgen Biotech Inc

Discipline:

Chemistry

Sector:

Professional, scientific and technical services

University:

University of British Columbia

Program:

Accelerate

Improving Financial Health in Canada

The goal of this partnership is to develop data-driven tools that will empower individual Canadians to improve their financial resilience and reduce their levels of financial stress. Individuals will complete a short questionnaire; based on their responses, will be assigned to one of three groups – financially stressed, financially coping or financially comfortable – giving them a clear picture of where they lie on the “financial wellness spectrum.” They will be informed of how changes to their response profile would lead to movement up or down the spectrum and will be pointed towards resources that can help them with their specific circumstances. The project will help the Canadian Payroll Association (CPA) cement its role as a thought leader with respect to financial well-being in Canada.

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Faculty Supervisor:

Matthew Davison;Adam Metzler

Student:

Yuhao Zhou

Partner:

Canadian Payroll Association

Discipline:

Other

Sector:

Other services (except public administration)

University:

Program:

Accelerate

Maternal Augmentation and Digital Empowerment Initiative in Tanzania (MADE-IT)

Shortages of skilled healthcare professionals and unequal distribution of healthcare professionals throughout the country are two key challenges causing unexpectedly high number of preventable maternal deaths in Tanzania. Hence, developing innovative solutions that take fewer resources but have a wider impact on Tanzanian midwifery education system is crucial to avert these deaths. Canadian Network for International Surgery (CNIS), with 25 years of midwifery teaching skills in Africa has developed a project called “Maternal Augmentation Digital Empowerment Initiative in Tanzania”- the main goal of the project is to examine the effectiveness of digital midwifery education compared to the traditional classroom based education in developing skilled nurses and midwives. If equally effective, the digital approach would be superior in that it is substantially less resource-demanding to teach a greater number of students; in addition, if demonstrated successful in Tanzania, this approach can be widely scaled in other countries with a similar context.

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Faculty Supervisor:

Stephen Hodgins

Student:

Rafat Noor

Partner:

Canadian Network for International Surgery

Discipline:

Epidemiology / Public health and policy

Sector:

Professional, scientific and technical services

University:

University of Alberta

Program:

Accelerate

Characterization and numerical simulation of precipitation in the climatic wind tunnel at Ontario Tech

Climatic wind tunnels (CWTs) can repeatedly control variables such as temperatures, humidity, rain, snow, etc., that cannot be controlled outdoors. This allows tests to be performed faster, in weeks instead of years, thus speeding up the product development cycle. However, generating realistic precipitation in a CWT is still a challenge, because it is not well understood and it is difficult to create repeatable precipitation as desired by industry. The objective of the proposed research is to characterize the precipitation in the CWT at Ontario Tech, and develop a numerical precipitation simulation model. The study will involve physical experiments to obtain parameters such as liquid water content, mean volume diameter, droplet number concentration, and particle size distribution are essential for precipitation characterization. They are essential for precipitation characterization and will also serve as validation data for the development of the numerical simulation model. Further, they will provide insight in the quality of precipitation generated in the CWT. The industry partner will gain insight in applying its analytics tools to precipitation data. This collaboration will also help the interns gain industry relevant skills.

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Faculty Supervisor:

Martin Agelin-Chaab

Student:

Olivia Shurtleff

Partner:

GlassHouse Systems

Discipline:

Engineering - mechanical

Sector:

Manufacturing

University:

Ontario Tech University

Program:

Accelerate

Subsurface Mapping and 3D Reconstruction of Silurian Clinton-Medina Groups, Southwestern Ontario

The Silurian age Clinton-Medina Groups is a succession of sedimentary rocks found across Ontario, in outcrop and in the subsurface. The history of the stratigraphy is complex, and therefore confusion exists relating the stratigraphy regionally in the subsurface across Ontario. The Clinton-Medina Group formations are important for Ontario’s energy sector, providing petroleum resources from natural gas pools found in Eastern Lake Erie. By properly describing and delineating the formations, using core, cuttings, and geophysical logs, this information can be used to interpret the current geological information of the units and accurately map the geographical extent of the formations. This information will contribute to the 3D geological model of the Phanerozoic geology of southwestern and southcentral Ontario, which will be used as a tool to aid in exploration, aid geologists in subsurface study, and provide a visual guide for government policy makers.

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Faculty Supervisor:

Jisuo JIn

Student:

Rhys H Paterson

Partner:

OGSR Library

Discipline:

Geography / Geology / Earth science

Sector:

University:

Western University

Program:

Accelerate

Sustainable Shipping – A roadmap to zero emission ambitions

Tackling climate change is a complex task, one that depends on transformation of different sectors. Maritime shipping is the transmission belt of the global economy and continues to account for the majority of imports and exports. It is recognized as an energy-efficient mode of transportation compared to road and air transport. Yet, maritime transport has increased by 250% over the past 40 years, resulting in the sector contributing to 3% of total annual man-made greenhouse gas (GHG) emissions. These emissions are expected to increase by 150%–250% by 2050 in business-as-usual scenarios, causing serious human health and environmental harm. More stringent global regulations have recently been introduced to mitigate emissions from ships. Maritime shipping is now expected to adopt innovative solutions to lower its impact on climate change. One alternative is to change fuels (i.e., a shift from the existing use of fossil fuels to clean fuels). Fuel choice is, however, uncertain, raising the critical question of which fuel is the preferable future marine transportation fuel. My research concerns improving knowledge and tools for effective corporate sustainability through collaborative decision-making.

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Faculty Supervisor:

David Gillen;Jane Lister

Student:

Mehrnaz Ashrafi

Partner:

Teekay

Discipline:

Other

Sector:

Transportation and warehousing

University:

University of British Columbia

Program:

Accelerate

Integrity and Analytics of Energy Market Data

ReWatt Power facilitates transactions of green energy derivatives/green attributes such as Alberta Carbon Offsets. The company uses a blockchain technology to manage all transactions on their platform. This way, all parties have access to the transaction history in a database they own, and the transactions are immutable. The first objective of this project is to ensure that source energy measurements are accurate before the resulting green attributes are permanently recorded. The second objective is to support customers in making decision on which energy derivative/green attribute should be used to maximize the monetary value of available measurements. This is a challenging prediction task that depends on attribute type, jurisdiction/geographical area, and time.

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Faculty Supervisor:

Petr Musilek

Student:

Caixiang Fan;Bahareh Lashkari

Partner:

ReWatt Power

Discipline:

Engineering - computer / electrical

Sector:

Energy

University:

University of Alberta

Program:

Accelerate

Building Systems Operational Dashboard and Analysis

Mircom is a Canadian Company that operates as a global player the building solutions sector and is the largest independent fire alarm and control system manufacturer in North America, with product lines spanning Fire Alarm and Emergency Audio, Communications, and Security and brands include Mircom™ Secutron™, and U.E.C.™ United Export Corporation. This project will boost Mircom’s competitiveness in global markets by using data effectively to improve operating margins. Using Mircom’s large repository of sales, manufacturing, supply chain, and inventory data, Mircom is collaborating with Seneca’s School of Software Design and Data Science to create advanced systems and tools to support manufacturing and supply chain operations. Objectives of this research are the development of a data lake architecture, which provides a consistent, reliable data repository for real time analytics, and the creation and training of machine learning and artificial intelligence-based tools to rapidly provide optimized pricing information and supply chain transparency.

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Faculty Supervisor:

Mark Buchner

Student:

Aracelli Elizabeth Tumbalobos Cubas;Saihong Xiao

Partner:

MIRCOM

Discipline:

Design

Sector:

Manufacturing

University:

Seneca College

Program:

Accelerate

Hidden Champion Businesses: The Way to Revitalize the Economy of Newfoundland and Labrador for Post-Covid-19 Era

The effect of a collapse in oil prices coupled with a province-wide lockdown due to the COVID-19 outbreak will have a significant impact on the economic future of NL. A spiking unemployment rate due to job losses in the services and tourism sector will be difficult to mitigate in the short to medium-term; if not handled, it could easily ripen into a larger societal issue in the long-term. The main emphasis of the research will be placed on analyzing Newfoundland and Labrador, seeking to discover some possible hidden champions in these markets as well as some of the key success factors that encourage the growth and success of globally minded hidden champions.

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Faculty Supervisor:

Chansoo Park

Student:

Mitchell Joyce

Partner:

Husky Energy Inc

Discipline:

Resources and environmental management

Sector:

University:

Memorial University of Newfoundland

Program:

Accelerate

Flexural behaviour of strengthened prestressed hollow-core slabs with bonded and unbonded prestressed carbon fiber reinforced polymer (CFRP) plates under various prestress levels…

…with bonded and unbonded prestressed carbon fiber reinforced polymer (CFRP) plates. The overall objective of this project is to enhance the strengthening efficiency of prestressed hollow-core slabs (PHCS) by using prestressed CFRP plates. More specifically, this project aims to investigate the behavior of the PHCS elements strengthened with prestressed CFRP plates. The application of the innovative patented anchor system developed at the University of Waterloo offers a good platform to facilitate the strengthening process in an efficient and cost effect way. The proposed research is expected to tackle problems of wide implication yet rarely addressed in the PHCS strengthening domain by introducing a site applicable strengthening technique for existing and in-service concrete structures.

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Faculty Supervisor:

Adil Al-Mayah

Student:

Amr Abdel Havez

Partner:

Fritz-Alder Precast Services

Discipline:

Engineering - civil

Sector:

Construction and infrastructure

University:

University of Waterloo

Program:

Accelerate

Interaction between cannabinoid drugs and sodium channels in diabetes/high glucose induced oxidative stress, neuroinflammation, and neurotoxicity – Year two

Diabetes mellitus, a common metabolic disorder, exhibits neuropathic complications that can eventually lead to disabling pain (Todorovic 2015). This is attributed to hyperglycemia/high glucose resulting in neuronal hyperexcitability (Todorovic 2015). Importantly, diabetes-evoked neuronal hyperexcitability and neurotoxicity can be caused by alterations in voltage-gated sodium channel (VGSC) expression (Hong, Morrow et al. 2004), resulting in changes in the sodium currents lowering the action potential threshold (Hong, Morrow et al. 2004, Chen, Wang et al. 2018). Interestingly, cannabinoids exert antinociceptive properties. In addition, both cannabinoid receptors, CB-1 and CB-2, are highly expressed in central and peripheral nervous systems, suggesting a fundamental role in nociception (Agarwal, Pacher et al. 2007, Rahn and Hohmann 2009). Also, estrogen (E2) loses its neuroprotective effect, or worsens neuronal injury in diabetic animals (Santizo, Xu et al. 2002). Thus, the current study aims to investigate the role of VGSC in high glucose-induced neurotoxicity, and whether high glucose modulation of VGSC can be altered using cannabinoids. Also, this study will investigate sex-determined modulation of cannabinoid/VGSC interaction in high glucose elicited neurotoxicity. Noteworthy, our results may identify novel molecular targets for alleviating neuropathic pain and solve the sex-specific exacerbation of neurological dysfunction elicited by diabetes.

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Faculty Supervisor:

Peter Ruben

Student:

Mohamed Fouda

Partner:

Akseera Pharma Corp

Discipline:

Kinesiology

Sector:

University:

Simon Fraser University

Program:

Elevate

The Effect of Degenerative Spine Disease on Neuromuscular Pain and Function

Despite its growing prevalence of chronic musculoskeletal disease in society, its cause is still poorly understood. Emerging research suggests that degenerative spine disease may be an important facilitator to the development of chronic inflammatory musculoskeletal disease. We aim to investigate the effect of degenerative spine disease on muscle inflammation, pain and dysfunction by using an animal model of experimentally induced spine osteoarthritis. The findings of this research have important implications to the partner organization (Ontario Chiropractic Association) as it will inform future basic research validating the important role of advancing spine treatment and prevention strategies and/or policies in the long term management of chronic musculoskeletal disease.

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Faculty Supervisor:

John Srbely

Student:

Kayla Fewster

Partner:

Ontario Chiropractic Association

Discipline:

Food science

Sector:

Other services (except public administration)

University:

University of Guelph

Program:

Accelerate

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