Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

31132 Completed Projects

2940
AB
5159
BC
837
MB
685
NL
882
SK
9291
ON
9695
QC
97
PE
601
NB
1161
NS

Projects by Category

Invariant Chain- Influenza A Fusion Adenovirus Vaccine Using M1 Gene

During primary immune responses, dendritic cells (DC) are the principal antigen-presenting cells (APCs) that initiate adaptive immune responses. DCs present pathogenic antigens (such as virus, bacterium and tumour) to induce CD4 and CD8 T cell responses via MHC-I and MHC-II pathways respectively. Recently, our lab has discovered that CD74 molecules not only promote MHC-II but also MHC I-antigen presentation. The MHC I-presentation is essential for CD8+ T cell mediated responses against viruses, tumours, self-antigens and allografts. This study is based on the discovery that CD74 mediates trafficking of MHC-I from the endoplasmic reticulum of DCs to endolysosomal compartments for loading with peptides and therefore CD74 has a critical function in DC presentation for priming MHC-I mediated CTL responses. This study chooses conserved influenza matrix 1 protein (M1) as antigen further CD74-antigen fusion constructs will be produced to further promote immune responses against influenza virus. This proposal will provide a potential influenza vaccine for BioMmune Technologies Inc.

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Faculty Supervisor:

Wilfred Jefferies

Student:

Partner:

Pascal Biosciences Inc

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program:

Accelerate

Assessing and modelling climate – pollutant interactions in marine food webs in the Pacific and coastal British Columbia, Canada

Healthy ocean food webs are key to the socio-economic viability of coastal communities in British Columbia. The Vancouver Aquarium’s Coastal Ocean Research Institute (CORI) was established in 2014 to provide an ongoing assessment of the health of Canada’s oceans. This project supports this strategic priority of the CORI initiative and advances the organization’s mission to conserve aquatic resources though display, interpretation, education, research and activities. This study will develop new sustainable Environmental Quality (EQ) objectives that will allow managers to explore the implications of different pollution abatement options on the value of ‘downstream’ coastal resources such as fisheries. Climate change and ocean pollution present a risk to the economies of coastal communities in British Columbia. New EQ Objectives that incorporate economic impacts associated with different management actions will improve the resilience of coastal communities into the future and advance the overall aim of enabling sustainable economic development on Canada’s west coast.

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Faculty Supervisor:

William Cheung

Student:

Partner:

Ocean Wise

Discipline:

Life Sciences

Sector:

Education; Professional, scientific and technical services

University:

The University of British Columbia

Program:

Accelerate

Roche Lake Eutrophication study

Roche Lake is the Roche Lake is the largest lake among 12 highly productive water bodies in the Thomson-Nicola region of BC’s southern Interior Plateau. It has experienced algal blooms over the past four years indicating a change in nutrient loadings to the lake. Roche Lake suffered a winterkill of more than 50% of fish due to low oxygen levels during the 2013-2014 winter, with low oxygen levels persisting throughout summer 2014. The algal blooms and impacts on fish populations indicate a significant level of eutrophication that needs to be addressed. The postdoctoral fellow will conduct a water quality study to evaluate causes of eutrophication in Roche Lake and evaluate possible management strategies to remediate conditions in the lake, as well as prevent other lakes in the region from experiencing negative environmental conditions.

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Faculty Supervisor:

Mark Johnson

Student:

Partner:

Freshwater Fisheries Society of BC;Habitat Conservation Trust Foundation

Discipline:

Physics

Sector:

Sustainability & the Environment; Water; Environmental Science and Technology

University:

The University of British Columbia

Program:

Accelerate

Organo-Tellurium Supramolecular Building Blocks

The student will travel to the Federal University of Santa Catarina (UFSC), Florianopolis, Brazil, for 12 weeks to develop the chemical synthesis of new organo-tellurium compounds whose molecules will be used as building blocks for large self-assembled structures with functional properties. This project will combine the expertise of I. Vargas-Baca (McMaster) and A L. Braga, hence starting collaboration in between their groups. This project will be a cornerstone in the graduate research project of the student. Fundamental knowledge derived from these investigations is central to many areas of materials chemistry, from open molecular frameworks capable of gas sequestration to molecular recognition and materials for photonic applications.

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Faculty Supervisor:

Ignacio Vargas Baca

Student:

Partner:

Federal University of Santa Catarina - to merge

Discipline:

Physics

Sector:

University:

McMaster University

Program:

Globalink Research Award

Improving mining efficiency through sustainable recovery of energy

Improving mining efficiency through sustainable recovery of energyA significant step towards sustainable mining would be non-traditional, but productive uses for the mine. In particular, uses that would allow them to provide value and jobs to the community both during mining and afteroperations cease. To help in achieving this goal there is potential positive use of both closed and operational mines to provide renewable geothermal energy from their mine waters. The relatively stable temperature of mine water can be exploited by the use of geothermal recovery loops coupled to heat pumps. During the winter, heat can be extracted from the water and supplied for space heating, and in the summer the process can be reversed, and the heat transferred back to the water to provide cooling. This project will combine direct measurements within mines with modeling to determine a feasible design for geothermal energy recovery in Canadian hard rock mines.

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Faculty Supervisor:

John Ashley Scott

Student:

Partner:

Discipline:

Engineering

Sector:

Mining

University:

Laurentian University

Program:

Accelerate

Federation of heterogeneous data sources for the linked data back-end in the Gold Fish mobile application

The overall goal is to create the backend of a mobile personal organizer that suggests professional events (conferences, colloquia, workshops, exhibitions) and contacts to establish while attending events, to members. Currently, the target audience are professionals in the biomedical domain. Given the need to feed data and meta-data from heterogeneous sources into the application, the industrial partner chose to implement the backend using semantic data management technologies. The main challenge at this stage is therefore to create the database (triplestore) that federates the chosen sources (social network profiles, event descriptions, domain terminologies, standards, etc.). Tools designed and co-designed by members of the academic team will be used and improved during this stage, in particular, methods for matching schemas and ontologies (domain models) originating in independent sources as well as for recognizing the alternative representations of the same entity (e.g. event) in independently created datasets. Thus, the academic team brings its joint expertise in the semantic technologies and its tools to the project that thoroughly benefits the industrial partner.

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Faculty Supervisor:

Petko Valtchev

Student:

Partner:

Goldfish Technologies Inc

Discipline:

Computer science

Sector:

Professional, scientific and technical services

University:

Université du Québec à Montréal

Program:

Accelerate

Reliability Modeling and Assessment of Power Systems Containing HVdc Links

The increased utilization of HVdc technology around the world has created the need for evaluating the reliability of power systems that contains HVdc facilities. For example, if the generation system is remote and it is connected to the load centre through HVdc links, the transmission may have a significant impact on the overall system reliability performance. Most of the research described in the existing literature focus on analyses of simple example power systems to illustrate the concepts, models and techniques in probabilistic reliability assessment of HVdc systems. Relatively scant attention has been given to incorporate the existing models and techniques in large practical power system reliability evaluations. The proposed research is targeted to take the advantage of calculation accuracy of an appropriate available tool such as Risk_A to develop a consistent and comprehensive method for reliability assessment of power systems containing HVdc links using the existing tool. The approach will be based on the utilization, modification or enhancement of existing reliability models proposed in various literature.

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Faculty Supervisor:

Aniruddha Gole

Student:

Partner:

Manitoba Hydro International Ltd

Discipline:

Engineering

Sector:

Professional, scientific and technical services; Utilities

University:

University of Manitoba

Program:

Accelerate

Antineoplastic evaluation of novel 3,5-bis(benzylidene)-4-piperidones

The supervisors and their colleagues have discovered a number of compounds which have greater toxicity towards different tumours than normal cells. The first step in the proposal is to determine the maximum tolerated dose of the compounds in mice after which the candidate anticancer agents will be administered to a special breed of mice in which a human colon cancer has been implanted. We hope to find if the tumour will have been destroyed or reduced in size. In addition, experiments are scheduled to determine if the compounds prevent the colon tumour migrating (i.e. metastasizing) to other organs of the mice. Bertech requires novel anticancer agents in order to attach antibodies to them which are specific for colon cancers. In other words, this application is part of a long term strategy of Bertech to provide therapeutics and diagnostics for patients with colon cancer.

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Faculty Supervisor:

J. R. Dimmock

Student:

Partner:

Bertech Pharma Ltd

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

University of Saskatchewan

Program:

Accelerate

Conception et mise en place d’un intranet dans une compagnie pharmaceutique à l’aide d’une approche expérience-utilisateur

Ce projet de recherche se concentre sur la conception et la mise en place d’un intranet dans une compagnie pharmaceutique à l’aide d’une approche expérience-utilisateur. « Les intranets sont des systèmes d’information basés sur la technologie du web, qui se positionnent comme des outils favorisant la productivité des employés qui les utilisent et la performance des organisations qui les implantent » (Grange et Barki, 2006, p. 149). Ces systèmes ont le potentiel d’aider les entreprises à devenir davantage concurrentielles. Toutefois, leur utilisation et leur efficacité dépendent de différents facteurs dont l’interaction entre l’utilisateur et la technologie. De plus, le contexte particulier des entreprises pharmaceutiques crée une situation paradoxale caractérisée par le désir de collaboration et de partage de l’information versus le respect du corpus réglementaire et des normes départementales pour protéger l’information. Pour toutes ces raisons, ce projet propose une approche innovatrice basée sur « l’expérience-utilisateur » où les utilisateurs sont placés au centre de la conception et de la mise en place de l’intranet afin de trouver un compromis au paradoxe et de favoriser l’utilisation du système.

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Faculty Supervisor:

Alina Maria Dulipovici

Student:

Partner:

PharmaScience (Montréal, QC)

Discipline:

Business

Sector:

Manufacturing; Professional, scientific and technical services

University:

HEC Montréal

Program:

Accelerate

Investigation of Electric / Compressed Air Hybrid Powertrain for Light Vehicle Propulsion

This project consists of two systems (Electric and Compressed Air) working together to power a vehicle. The electric system is the primary system and if its power source is depleted then the compressed air system can provide power for hours to get the vehicle to the next refilling station. The two systems are recharged during deceleration of the vehicle and during operation of the air system. During operation of the air system the expelled air will travel to a compressor which will refill the tank and then on to an electric generator which will recharge the electric system. When both systems are near discharged then the vehicle can be recharged/refilled at a recharging/refilling station. The multiple layers of redundancy are built into the design by having two separate systems and the electric system separated into two systems. The air system also has the capability of being separated into two systems if needed.

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Faculty Supervisor:

Ibrahim Dincer

Student:

Partner:

Antrobus Consulting Ltd

Discipline:

Engineering

Sector:

Manufacturing

University:

University of Ontario Institute of Technology

Program:

Accelerate

Borders in Globalization – Pre-contact Boundaries of Aboriginal Peoples in the Lower Great Lakes

This project is a component of the Borders in Globalization initiative, an international network of academic partners which is engaged with non-academic organizations that are involved in the study and management of borders and borderlands in Canada and worldwide. The basic goal is to build excellence in the knowledge and understanding of borders. The contribution of this study will be a comprehensive, thematically organized bibliography pertaining to the nature and functioning of borders and boundaries amongst non-industrial societies with a focus on the archaeological and early historical record of Algonquian and Iroquoian societies indigenous to the Lower Great Lakes. This bibliography will ultimately be used by two principals of the partner organization (Archaeological Services Inc.), in collaboration with the student intern, to author a detailed academic paper on the subject as an anthropological and culture historical contribution to the overall Borders in Globalization enterprise.

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Faculty Supervisor:

Neal Ferris

Student:

Partner:

Archeological Service Inc;Archaeological Services Inc

Discipline:

Sociology

Sector:

Professional, scientific and technical services

University:

Western University

Program:

Accelerate

Évaluation économique en pharmacogénomique

Le développement de la pharmacogénomique a permis notamment l’identification de biomarqueurs permettant de mieux cibler les patients pouvant bénéficier de certains traitements ou d’estimer le risque d’être éventuellement atteint d’une certaine maladie. Les tests pharmacogénomiques découlant de la découverte de ces biomarqueurs devront être évalués pour leur utilité clinique, mais aussi pour leur impact économique. En effet, au même titre que toutes autres interventions en santé, l’adoption d’un test pharmacogénomique en pratique courante devra être sujette à une évaluation économique. Les tests pharmacogénomiques et leur contexte d’utilisation comportent des caractéristiques particulières qui influencent leur impact économique. On note entre autres, la sensibilité et la spécificité du test, la proportion des différents génotypes dans la population et les conséquences du résultat obtenu avec le test.
Ce projet de recherche consiste à développer des modèles pharmacoéconomiques pour évaluer l’impact économique de tels biomarqueurs et tests pharmacogénomiques. Les résultats de ce projet de recherche contribueront à une utilisation plus efficiente des ressources en santé.

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Faculty Supervisor:

Céline Fiset

Student:

Partner:

Peripharm

Discipline:

Life Sciences

Sector:

Manufacturing; Professional, scientific and technical services

University:

Université de Montréal

Program:

Accelerate

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Mitacs — Return on Innovation

Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.