L’objectif principal de cette étude pilote est d’élaborer les protocoles de conception, de fabrication et d’application clinique de la thérapie de Klearway par orthèse endobuccale chez l’enfant. En évaluant les dossiers orthodontiques (questionnaires, radios et modèles d’étude dentaire) ainsi que les niveaux d’oxygène sanguin avant et après le traitement, il devrait être possible de définir […]

Computer vision and artificial intelligence provide unprecedented opportunities to realize new image-based biomarkers with the potential to drive precision drug development and personalized medicine; particularly in degenerative disease of eye and brain, where tissue sampling is not possible and where no treatments exists. This research project will deploy AI models for multiple tasks including segmentation, […]

The human oral cavity contains over 700 different bacterial species. In healthy people, these bacteria are living in harmony and not likely to cause diseases. However, sometimes this bacterial balance is disturbed as the oral pathogenic bacteria start to overgrow causing many oral implications such as halitosis, sore throat, dental caries and gingivitis. A promising […]

Correction of misaligned teeth requires orthodontic braces treatment. Cone-beam computed tomography (CBCT) has been routinely used in orthodontic diagnosis and treatment planning in recent years. Its three-dimensional capability to view images has a significant advantage over traditional 2D X-rays. However, CBCT typically delivers more radiation than conventional dental 2D X-rays. As children and adolescents are […]

Oral cancer (OC) presents a global burden on society and the healthcare system with high incidence rates and poor prognosis. Despite the oral cavity being easily accessible for visual assessment, lesions are often detected at an advanced stage when the prognosis is poor and radical interventions are necessary. An invasive biopsy of a clinically suspicious […]

The overall objective of this pilot study is to develop design, manufacturing and clinical protocols for the application of Klearway’s oral appliance therapy to a child population. By evaluating orthodontic records (questionnaires, x-rays and dental study models) together with blood oxygen levels before and after treatment, new applications for Klearway’s oral appliance use and new […]

  The proposed project will research the therapeutic effects of low intensity pulsed ultrasound on dentoalveolar structure on dogs.  The main research problems to be addressed by this project are: (1) study the effects of LIPUS (Low-intensity pulsed ultrasound) on the tooth root tissues (cementum and pulp) when moved orthodontically, and (2) study the effects […]

The loss of bone is a massive burden on the health care system and severely impacts the quality of life of several hundred million people. The need for alternative strategies to replace or regenerate bone tissue is overwhelming. We are proposing a completely new approach to the engineering of bone using a ―cocktail‖ of genetically […]

The loss of bone is a massive burden on the health care system and severely impacts the quality of life of several hundred million people. The need for alternative strategies to replace or regenerate bone tissue is overwhelming. We are proposing a completely new approach to the engineering of bone using a “cocktail” of genetically […]

This research and development project intends to improve the performance of a dental implant stability measurement (ISMS) device made by Prefail Dental Solutions Inc. The technical improvements proposed by this project includes (i) developing an impeoved and reliable signal processing technique, (ii) designing a calibration unit, (iii) designing a new tip for the ISMS clinical […]

Most of the available toothpastes are designed to manage tooth decay. Older individuals, however, suffer from gum diseases that caused by accumulation of plaque and tartar on teeth or implants. The most common way of cleaning the teeth is with a brush and toothpaste. However, even though major companies offer a wide range of products […]

Dental caries is a major health hazard in the general population worldwide. Fluoride-based formulations are conventionally used to resolve this problem but they present certain important disadvantages, which has been overlooked. Here we propose to develop and characterize a non-fluoride based dental varnish using natural product conjugated nanoparticles that holds the potential of inhibiting bacterial […]