Probiotics Alleviating Depressive Symptoms (PADS)

Recent evidence shows there is extensive and direct communication between the brain and gastrointestinal tract, where nutrients are absorbed, and that intestinal microbiota have a role in healthy brain function. This study aims to look at the effects of probiotics, live bacteria that inhabit the gut and can help improve your health, on the mood, […]

Read More
Engineering Synthetic D-Proteins as Novel and Transformative Molecular Therapeutics Against Cancer Targets

Proteins can exist in two forms: left-handed (L) or right-handed (D); however, for indeterminate reasons life on this planet only uses the L-form. When studied in more detail, both protein forms possess identical physiochemical and biological properties. Yet, D-proteins show minimal proteolytic degradation and fail to elicit immune responses in animals, due to their unnatural […]

Read More
Toxicity of nanomaterials to Amazonian fish in different water types

The Negro and Solimoes rivers in the Amazon Basin house an incredible diversity of fish, up to 3000 species, and are critical to the economies and cultures of the communities through which they run. The waters of the Rio Negro are clear and black, with a high concentration of dissolved organic material but almost no […]

Read More
Nitrous oxide emissions from fertilized cotton (Gossypium hirsutum L.) under a drip drip irrigation as influenced by nitrogen fertilizer placement depth and rate.

Irrigated cotton (Gossypium hirsutum) in arid areas of China receive very high nitrogen inputs of up to 240 kg/ha-1. The crop also receives large inputs of irrigation water mostly under drip irrigation system. This system will be used to determine the contribution of processes of nitrification and denitrification (microbial processes involved in the production of […]

Read More
Application of genomics to improve performance traits in mink

Understanding the genes involved in variation of complex traits is termed genomics. Genomics can provide new tools that can be used to easily and accurately select animals for economically important traits. This exercise will generate large numbers of DNA markers that can be used to find the genes that explain variation in such traits. These […]

Read More
Exploring home range and habitat use during the breeding season of the Bicknell’s thrush (Catharus bicknelli) in New Brunswick Clear-cuts

The Bicknell’s thrush (Cathurs bicknelli) is a rare songbird with the most restrictive breeding range in North America. The Bicknell’s thrush spends its summer months breeding in high elevation, stunted growth forests – a habitat that the species specializes in. In New Brunswick, there has been a documented population decline of 11.5% per year since […]

Read More
Filling in the gaps of the IMD immune pathway of the kissing bug Rhodnius prolixus

Rhodnius prolixus is a hemathophagous insect that has served for decades as a model to study insect physiology. Rhodnius prolixus is also a major vector of Trypanosoma cruzi, the etiological agent of Chagas disease that kills 45,000 people annually and affects over 8 million people worldwide. The genome of R. prolixus contains ~15,500 predicted protein-coding […]

Read More
In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem […]

Read More
Biomolecular Quantitation and Structure Analysis to Accelerate Development of New Vaccines

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of […]

Read More
The role of cyclodextrins in repairing dysfunctional lung surfactant

My work will provide an important insight of the newly developed S1229. Cyclodextrins (S1229) are cyclic molecule composed of 7-sugars, with a unique structure. S1229 forms a hydrophobic core, which interacts with cholesterol and phospholipid by-products and removing them from the membrane. SolAeroMed has shown that S1229 was able to repair lung surfactant function. Lung […]

Read More