Impact of dietary fibre and immune challenge on threonine requirements and pig robustness

Sub-clinical disease results in reduced growth and less efficient use of nutrients, resulting in substantial impact on profitability of pork producers. With the elimination of in-feed antibiotics for growth promotion it is increasingly important to understand the interaction between nutrition and health and nutrient requirements during disease challenge events. Feeding high-fibre feedstuffs reduces the efficiency […]

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Implementation of a chip-based MDTMA platform for evaluating prostate cancer treatment response and mode of action.

Prostate cancer will affect 1 in 7 Canadian males. While the number of therapeutic options is increasing, matching each patient to the right therapy remains as the challenge for a personalized approach to patient management. Currently, most of the attention has focused on identifying biological tags that can predict patients response. We have developed an […]

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Synchronization of ovulation to improve the efficiency of an in vitro embryo production/embryo transfer program in commercial operations in cattle

In vitro embryo production and embryo transfer (IVP/ET) is a technique that has been developed in cattle for genetic selection to enable rapid improvement in commercially important traits. Technological advances have resulted in a significant increase in the commercial use of IVP/ET in recent years, and have made this one of the fastest growing sectors […]

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Synchronization of ovulation to improve the efficiency of an in vitro embryo production/embryo transfer program in commercial operations in cattle – Year two

In vitro embryo production and embryo transfer (IVP/ET) is a technique that has been developed in cattle for genetic selection to enable rapid improvement in commercially important traits. Technological advances have resulted in a significant increase in the commercial use of IVP/ET in recent years, and have made this one of the fastest growing sectors […]

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Development and commercialization of novel reference material for food allergen and gluten proficiency testing

The planned research program aims to address an existing gap: the lack of commercial availability of reference materials for food allergens to be used in the context of analytical method development, validation and performance testing. In particular, naturally incurred samples representing food matrices where priority allergens are likely to occur, in a controlled and calibrated […]

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Development and commercialization of novel reference material for food allergen and gluten proficiency testing – Year two

The planned research program aims to address an existing gap: the lack of commercial availability of reference materials for food allergens to be used in the context of analytical method development, validation and performance testing. In particular, naturally incurred samples representing food matrices where priority allergens are likely to occur, in a controlled and calibrated […]

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Validation of food allergen analytical methods and their incorporation in food process control practices – aiming for more predictable, risk-based quality management systems for processed foods -Year2

The planned research aims to validate food allergen testing tools from r-Biopharm Canada, and their incorporation in novel quality-management systems used in food production. The first part of the project consists in developing validation criteria for allergen methods under the auspices of the Association of Official Analytical Communities (AOAC) and apply these new requirements for […]

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Cibler l’aneuploïdie dans le cancer épithélial de l’ovaire par la modulation de la GTPase Ran. Implications thérapeutiques

Au Canada, le cancer épithélial de l’ovaire (CEO) est à l’origine de 1500 décès par an. Etant donné qu’aucune amélioration de la survie des patientes n’a été observée durant les dernières décennies, il devient impératif de développer de nouvelles stratégies thérapeutiques de ce cancer. Le CEO est caractérisé par une hétérogénéité accrue qui s’installe dès […]

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Cibler l’aneuploïdie dans le cancer épithélial de l’ovaire par la modulation de la GTPase Ran. Implications thérapeutiques – Year two

Au Canada, le cancer de l’ovaire est le deuxième cancer gynécologique le plus commun. Étant donné que cette maladie est asymptomatique pendant les stades précoces, plus de 70% des patientes sont diagnostiquées à des stades avancés. Le but de notre projet est de proposer de nouvelles options thérapeutiques du cancer de l’ovaire. Il est établi […]

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Développement d’une SnapChip multiparamétrique pour l’étude du diabète

Une bonne compréhension de la biologie derrière le développement du diabète de type II est indispensable à son traitement. Malheureusement, c’est une maladie complexe dans laquelle de multiples protéines sont impliquées dans le maintien du taux de sucre dans le sang, débalancé lors du diabète. Il existe différentes approches, dites « multiplex », pour mesurer […]

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