Development of an Al first molecular database to accelerate drug discovery

Using simplified language understandable to a layperson; provide a general, one-paragraph description of the proposed research project to be undertaken by the intern(s) as well as the expected benefit to the partner organization. {100 – 150 words) The project aims to develop a molecular compounds database to accelerate drug discovery. Compounds shared by chemical providers […]

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Application of Topology Optimization for Efficient Composite and Additively Manufactured Structures

Additive manufacturing offers new opportunities for designing high performance composite structures. However, sophisticated numerical approaches are required to tackle the complex task of designing structures which take full advantage of additive manufacturing capabilities. The proposed research project aims to apply topology optimization, a numerical approach capable of determining the best shape of a structure, to […]

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Bacterial P450 engineering for production of high value antibacterials

Many pharmaceutical drugs are synthesised by traditional organic routes, however this approach is limited to the scope of traditional chemical catalysts that often yield predictably similar products. Pharmaceutical synthesis is moving towards alternative synthetic routes such as biosynthesis in order to develop sustainable, cheaper routes of novel small molecule production. This is crucial for antibacterial […]

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Field evaluation of bacilin 20: Herbicide stress and accelerated flowering

Plants are always associated with a well coordinated and beneficial community of microbes – the phytomicrobiome; this plus the associated plant forms the holobiont, the entity that provides crop yield. There is considerable communication between the phytomicrobiome and the plant, often in through signal compounds. Bacilin 20 is a small protein produced a Bacillus thuringiensis […]

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Towards Automating Ore Sorting with Rich Sensors

To make mining more efficient and environmentally friendly, transportation of rock should be minimized. Ideally we would only transport those rocks that contain economically extractable amounts of minerals. MineSense has developed sensors that can detect the level of minerals in rocks and, in particular, can detect very low levels with high accuracy. This proposal is […]

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THE USE OF WEARABLE VITAL SIGNS SENSOR TECHNOLOGY FOR EARLY PHYSIOLOGICAL DETECTION AND TRACKING OF VIRAL RESPIRATORY TRACT INFECTIONS

BACKGROUND: Viral respiratory tract infection (VRTI) is the most common illness in humans, resulting in a total economic impact of $40 billion annually in the United States. Taking into consideration the current novel coronavirus pandemic – impacting billions of people around the world, compromising the global economy, and putting extreme pressure on healthcare systems – […]

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The Use Of Wearable Vital Signs Sensor Technology For Early Physiological Detection And Tracking Of Viral Respiratory Tract Infections – Year two

BACKGROUND: Viral respiratory tract infection (VRTI) is the most common illness in humans, resulting in a total economic impact of $40 billion annually in the United States. Taking into consideration the current novel coronavirus pandemic – impacting billions of people around the world, compromising the global economy, and putting extreme pressure on healthcare systems – […]

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Development of Pharmacological Probes for Road-Mapping WD40 Domain Proteins

Since the dawn of the human genome sequencing in 2003, great hopes have been put into the development of new therapeutics and personalized medicine tailored on individual DNA profiles. Nonetheless, progress in these fields has been slow, mainly due to the focus of the research community on only a small number of genes and proteins […]

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High Performance Machining System- Optimization, Condition Monitoring and Control

The terminal objective of this cluster project is to achieve high performance machining of difficult-to-cut materials, in terms of reduced production cost, increased productivity, as well as achieving pre-defined part quality attributes and maximizing the utilization of the machine tool. To achieve this goal, an intelligent unmanned machining system need to be developed. The following […]

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Adapting Retail Practices to the Post-Pandemic Landscape

We will work with Alimentation Couche-Tard (ACT) to adapt retail practices to the post-pandemic world. Consumer behaviour has dramatically evolved due to the recent COVID-19 pandemic. Consumers are spending less time shopping and they aim to minimize physical contact. This shift in purchasing behaviour will generate unique data that may allow us to develop new […]

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Interactive Image Segmentation for the DiyoramaMobile Engine

Hololabs Studio Inc. is developing a mobile platform called Diyorama, which enables users to arrange images into interactive 3-~ scenes with an aesthetic similar to paper craft and collage art. Users can include images from their photo libraries, social networks, or image search results in order to create customized playable scenes from existing content. The […]

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