Numerical and Experimental Investigation of Drive Motor Thermal Performance

This research project is related to the development of innovative solutions to enhance thermal performance of self-contained DM systems. The project will be carried out in collaboration with Van der Graaf Inc. (VDG), which is a Canadian company located in Brampton, Ontario. A long-term plan has been developed by the applicant and the industrial partner. […]

Read More
Leveraging linked, person-level health information to inform resident safety and a risk management framework within retirement homes in Ontario, Canada

The retirement home sector in Ontario is rapidly expanding, given the need for assisted living services to support an aging population, coupled with health system issues related to hallway health care and a deficit of long-term care capacity. However, there is no research on this sector to inform policies related to risk assessment, quality of […]

Read More
Investigations into the mechanism of action and potential in idiopathic pulmonary fibrosis of the novel ruthenium based therapeutic BOLD-100

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease lung disease with unknown cause. There are limited treatment options for IPF and investigations into new treatment options is needed. BOLD-100 is a clinical-stage small molecule that is currently being investigated as a treatment option in oncology and viral infections. The pathway that BOLD-100 impacts, […]

Read More
COVID-19 Infection and Epithelial Cell Markers

Covid-19 has emerged as a major health concern in 2020, with a mortality rate of 11%. Covid-19 is due to a new coronavirus, SARS-CoV-2, which enters the human body through a receptor called ACE-2 in the airway. Asthmatics are usually at increased risk for viral infections, which exacerbated their asthma symptoms, however early clinical studies […]

Read More
Evaluation of recombinant bovine herpes virus-1 as a platform for novel cancer immunotherapy development

The most recent breakthroughs in cancer treatment are based on understanding that our immune system can be activated to attack tumours. While first achieved using antibody drugs called “checkpoint inhibitors”, this new paradigm of activating a cancer patient’s own immune system is also possible using viruses, an emerging field known as oncolytic virus (OV) therapy. […]

Read More
Investigation of IL-5R? expression on ILC2 as a target for Benralizumab

A newly identified group of cells termed type 2 innate lymphoid cells (ILC2s) have been discovered in the past decade. Increasing evidence supports the view that ILC2s play a central role in driving the cellular changes in the airways of asthmatic subjects. ILC2s are increased in severe asthmatics with uncontrolled inflammation despite being on the […]

Read More
On-Chip True Time Delay Optical Beamforming for RF Phased Arrays

Our space-based radio-frequency communication is suffering from the use of simple phase shifters. Its bandwidth capability is limited, ultimately reducing the satellite’s capacity and the system’s service availability. Most electronic beamforming implementations are bulky, frequency dependent and they consume a significant amount of power. To replace those electronic components, structures which guide light on microchips […]

Read More
Ontario’s Digital Research Infrastructure Needs Assessment And Capacity Building

Researchers in Ontario use various digital tools, technologies, and services to help with their work. This includes software, hardware, and people with technical expertise. Compute Ontario helps ensure that researchers have access to the digital resources and services that they need to complete their research. The demand for these resources is growing in Canada, and […]

Read More
Development of Ultra High Strength (>1GPa) Vanadium Microalloyed Dual Phase Steels For Automotive Lightweighting

Reducing CO2 emissions and improving the crash-resistance of passenger vehicles are two objectives that Canadians all share. One excellent technique to do both at the same time involves substituting existing body components with new advanced high strength steels (AHSS) that are produced with higher tensile strengths (better energy absorption and better anti-intrusion properties) and thinner […]

Read More
In-situ performance verification of the Pizza Oven Waste Energy Recovery (POWER) System within Restaurant Environments

The demonstration project provides the opportunity to substantiate the ability of the POWER system to repurpose wasted thermal energy from a cooking appliance’s exhaust gases and improve the overall restaurant energy performance across three Pizza Pizza locations within the Greater Toronto and Hamilton Area (GTHA). The data collected through the project will also allow for […]

Read More