Cryptosporidiosis is the infection by the parasite Cryptosporidium that can cause life-threatening diarrhea in children

This project aims at understanding the role at a cellular level, of a protein called Trmt2a,b in the repair of DNA in the context of cancer and inflammation. We will study a particular set of blood samples obtained from a cohort of patients affected by acute lymphoblastic leukemia (ALL), a form of blood cancer, where […]

Heart failure is a common cardiovascular disease that is becoming even more prevalent worldwide. The current gold standard treatment for end-stage heart failure is heart transplantation. However, heart transplant therapy is a limited option due to the available number of donors, thus heart pumps emerged to offer circulatory support to patients in the heart transplant […]

Uveal melanoma (UM) is the most common primary ocular tumor in adults. UM is treated by removing the eye (enucleation) or by local radiation therapy. Despite effective treatments for the ocular tumors, about 50% of patients develop metastasis, which are frequently lethal. Genetic profiling is used to study the molecular changes that occur and is […]

The present proposal seeks to address an urgent need to evelop new trugs that target metastatic cancer with high efficacy and specificity. The type 1 insulin like growth factor (IGF-I) is a growth-promoting factor implicated in cancer cell growth and metastasis. The receptor for IGF-I has been validated as a target for anticancer therapy in […]

The goal of this research project is to establish a working robotic “hand”, or gripper, that will be able to perform surgical instrument handoff to operating room staff members during surgery. This project will involve a both McGill University and Kinova, the partner organization. Kinova will benefit from this project through increased collaboration with academia, […]

As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient’s perspectives and experiences into research and clinical decision-making. In abdominal surgery, this is currently precluded by the lack of PRO measures specifically developed and validated in […]

We aim to develop human bone extracts mixed with commercially available bone putty and prepare customized 3D print materials, both of which are infused with anti-cancer drugs. These bone substitutes could be used to fill and stabilize the large empty spaces and to locally deliver anti-cancer drugs that kills any remaining tumor cells and promote […]

When two brains are engaged in a social interaction, specific brain activity emerges that causes the two brains to become ‘in sync’. This discovery was made possible by ‘hyperscanning’, a technique where two people are simultaneously scanned in two Magnetic Resonance Imaging (MRI) scanners to record their brain activity while interacting with each other in […]

Cancer is associated with weight loss, decreased muscle strength and inflammation. This has a tremendous impact on daily activity, autonomy and quality of life, involving both patients and care-givers. I previously worked on a preoperative intervention called ‘pre-habilitation’, a personalized exercise and nutritional supplementation delivered before surgery. The main idea is to prevent postoperative complications […]