Lipid-made nanoparticles are small delivery vehicles that can encapsulate therapeutics like mRNA and drugs. These tiny containers help to protect therapies until they are delivered into cells where they have better effects. A huge portion of the worldwide population have them in their bodies, thanks to mRNA COVID19 vaccines from Pfizer and Moderna. A lot […]

In 2018, Canada legalized the use of recreational cannabis. Despite legalization, there are still many things we do not know about how cannabis can impact our health. It is important that scientists study what cannabis does to our bodies so that Canadians can be informed consumers. A common way to consume cannabis is to use […]

Couples with infertility and recurrent miscarriage suffer from not being able to have children. They visit the best specialists in different medical centers, sometimes in different cities and countries seeking help before their biological clock declines and many do not achieve pregnancies. The overarching goal of this project is to identify novel genes for female […]

There is growing evidence that outcomes after colorectal surgery are improved with the use of perioperative interventions combined into an enhanced recovery program (ERP). Encouraging patients to achieve specific daily nutrition and mobilization goals postoperatively is an important aspect of ERPs; however, it is not known whether the achievement of these goals needs to be […]

Oocyte cryopreservation is imperative for assisted reproductive technologies (ART). It offers cancer patients to preserve their oocytes for future fertilization, flexibility in the timing of infertility treatment, and the potential for establishing oocyte banking. However, the currently available protocol is limited because the oocytes after cryopreservation have lower ability to develop into viable embryos (developmental […]

The incidence of female infertility is on the rise in Canada, afflicting up to 17% of woman between the ages of 18 to 34 and with a considerably higher rate of occurrence in woman over 34. Many infertile women are now turning to assisted reproductive technologies (ART) to facilitate conception and child bearing. Female oocyte/egg […]

and quantitative clinical assessment of the cardiovascular system. However, the clinical utility of CMR is impaired by the need for local expertise, the technical complexity, and time requirements required to perform it. Recently, several new techniques have radically changed the spectrum of CMR applications. The major pivotal change of CMR acquisition techniques has been the […]

We propose to develop in collaboration with Medtronic Canada a bioceramic drug delivery system for the local controlled release of Biphosphonates (BP) – drugs that prevent bone resorption – to promote both tumor inhibition and bone regeneration at the site of bone tumor resection, eliminating the need for high systemic doses and side effects associated […]

Strokes and myocardial infarctions, caused by the rupture of unstable atherosclerotic plaques in the carotid and coronary arteries, are the leading causes of death world-wide. Current clinical guidelines recommend surgical removal of plaques based solely on the degree of artery stenosis. However, stenosis alone is an incomplete determinant of stroke/heart attack risk, leading to suboptimal […]

Influenza vaccination programs aim to protect the population during seasonal outbreaks and pandemics but current vaccines face a number of challenges including inefficient production, variable immunogenicity and rapidly waning protection. To address some of these challenges, the Quebec-based biopharmaceutical company Medicago has developed a technology for producing influenza virus-like particle (VLP) vaccines in plants. This […]

La chorioamniotite, infection ascendante de la grossesse est une cause majeure de prématurité et de paralysie cérébrale chez les enfants prématurés. Le laboratoire du Pr Sébire (Research Institute of McGill University Health Center, Montréal) a mis au point un modèle de rates gestantes présentant une chorioamniotite induite par du streptocoque du groupe B. Au cours […]

Online health promotion programmes must be shown to improve health and promote a healthy lifestyle of the target population. These programmes are inexpensive and available to everybody. The company has previously created an OHPP for Canadian Veterans in order to encourage a healthy lifestyle among Canadian Veterans. We will now develop a second platform to […]