Changes in Pediatric RSV Hospitalizations after the COVID-19 Pandemic, 2022-2023, Canada: An Active Surveillance Study

The proposed project will be the largest ever study of RSV associated hospitalizations to Canadian tertiary pediatric hospitals. Cases are identified via our national active surveillance program for vaccine-preventable diseases, the Canadian Immunization Monitoring Program ACTive (IMPACT). IMPACT’s pediatric hospital-based active surveillance network provides a rich source of data with rigorous quality control processes and […]

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L2M – Osteoprobe: A handheld medical device probe for the intraoperative assessment of bone cancer to avoid cancer relapse

Our project aims to develop Osteoprobe, a smart medical device that helps doctors identify cancerous bone tissue instantly during surgery. It uses light and electrical signals to tell the difference between healthy and cancerous bone, providing quick and accurate results without the need for extra tests. This will help surgeons make better decisions, remove only […]

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Developing a robust AI pipeline for clinical trials using digital devices: Integrating sample size estimation, data quality assessment, and AI for enhanced medical screening

Cardiovascular disease is a major global health challenge, and early prevention is crucial to reducing its impact. This project explores how wearable devices and artificial intelligence (AI) can improve early detection and prevention of heart disease. Wearable sensors continuously collect health data, but challenges such as missing information and inaccurate readings limit their reliability in […]

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An IGF-Trap for cancer therapy

The Brodt laboratory engineered and developed a novel IGF-targeting molecule (the IGF-Trap) with otent anti-cancer effects. The objective of this project is to optimize the use of this potential drug in re-clinical cancer models and develop sensitive biomarkers for assessing and predicting its effect. In addition, the effect of this inhibitor on pancreatic cancer growth […]

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Assisted Video Laryngoscopy (AVL): A Novel Method of Endotracheal Intubation Using a Next-Generation Video Laryngoscope with Artificial Intelligence Assistance

The research project aims to improve the safety and effectiveness of endotracheal intubation, a critical medical procedure. Endotracheal intubation involves inserting a breathing tube into a patient’s airway using a laryngoscope and is commonly required for surgery and in emergency situations. The research intern will study a novel technique called assisted video laryngoscopy (AVL), achieved […]

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L2M – A diagnostic innovative handheld probe for the intraoperative assessment of bone cancer to avoid cancer relapse

Our proposed project involves developing the Osteoprobe, a cutting-edge tool designed to help surgeons accurately identify and remove bone cancer during surgery. By using advanced technology, including spectroscopy and artificial intelligence, the Osteoprobe provides real-time information, ensuring that only cancerous tissue is removed and healthy tissue is preserved. This innovation is expected to significantly improve […]

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Strontium loaded 3D printed scaffolds for improved bone regeneration

Strong evidence exists indicating the therapeutic potential of strontium in bone health and regeneration, and perhaps treating metastatic bone disease. Since current standard treatments of large bone defects can still result in poor outcomes (whether using autografts, allografts, ceramic or acrylic cements). New technologies and advances in 3D printing with ceramics and other blended bioactive […]

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Elucidating the Environmental, Socioeconomic and Occupational risk factors of Psoriasis: the ESO-PsO study

Skin diseases, like psoriasis, are a growing global health concern, especially in North America. Understanding the factors that increase the risk of these diseases are important for prevention and treatment. The introduction of targeted and biologic agents has significantly transformed the treatment of prevalent skin disease like psoriasis in recent years. However, due to their […]

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Investigating the Effects of High-Intensity Interval Training Based Multimodal Prehabilitation on Inflammatory and Immune Markers in Patients with Non-Metastatic Non-Small Cell Lung Carcinoma – A feasibility study

Lung cancer is a significant health concern worldwide, and a common type called non-small cell lung carcinoma (NSCLC) is responsible for many cases. Surgery is the preferred treatment for early-stage NSCLC, but it can lead to complications after the operation, affecting patient recovery. In addition, inflammation before surgery has been linked to worse outcomes in […]

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Caregiver Skills Training

Early intervention services for children with developmental delays, disorders, and disabilities are important, especially as early as possible in life, to provide the best chances for the child to thrive. Yet, children with these conditions do not receive timely care because relevant services are inaccessible due to long wait-times and high cost for families. The […]

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Adaptation, traduction et validation d’une mesure de l’expérience rapportée par les patients pour les enfants et les jeunes dans le contexte canadien

Contexte : Les mesures de l’expérience rapportée par les patients (PREM) évaluent objectivement la perception des soins par les enfants et les jeunes (CYP). Le seul PREM pour la chirurgie pédiatrique développé avec et pour les enfants a été créé à Londres, au Royaume-Uni. Étant donné l’absence d’instruments nord-américains similaires, nous avons cherché à adapter, […]

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