Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose, which leads to serious damage to the heart, blood vessels, eyes, kidneys and nerves over time. It is estimated that around 10% of Canadians have diabetes, which is 1 of the 10 leading causes of death globally. While diabetes is highly prevalent, […]

Positional plagiocephaly is an increasingly common form of cranial deformity in infants, affecting approximately 40% of infants under the age of 1. While it is not associated with developmental defects or learning impairments, there can be long term aesthetic implications for deformity that is not appropriately addressed early in life. Early identification of plagiocephaly and […]

Early onset scoliosis (EOS) leads to severe, progressive three dimensional deformity of the spine in growing children, which is corrected either by external bracing or surgical placement of rods adjacent to the spine. Mice deficient in signaling through the type three fibroblast growth factor receptor (FGFR3-/-) develop scoliosis by four weeks, which worsens progressively with […]

This project aims to improve how people with Parkinson Disease (PD) walk. Typically, people with PD develop a shuffling gait and limits walking for health and fitness and can also lead to falls and fractures. This project is based on a SMART sensor, Heel2ToeTM, that attaches to the outside of the shoe and gives a […]

One of the most critical components of ultrasound-guided nerve blocks is the accurate detection of a nerve within an ultrasound image. Trying to classify the various types of tissue in a noisy, greyscale ultrasound feed is a very daunting task. Therefore, a software solution would help doctors to perform the procedure in a precise and […]

The aim of radiation therapy is to give a high radiation dose to the tumour while minimising the dose to healthy tissues. Radiation therapy has seen significant progress and innovations in recent years. Implementation of these newly developed treatment techniques in the clinic require high accuracy in dose delivery due to the relationships between absorbed […]

Anterior cruciate ligament (ACL) injuries are one of the most frequent injuries among athletes. Currently, the only way to predict an individual’s risk of incurring an ACL injury is through prohibitively expensive motion analysis laboratories. There is a critical need to develop novel tools that improve knee-health and are well-received by the athletic community. This […]

Epidural injection is a medical intervention to inject therapeutics directly at the vicinity of the spinal cord and the nerves branching from it. This procedure may be performed for regional anesthesia, e.g., for painless labour, or pain management, e.g., for persistent low back pain. For epidural injection, a long thin needle is inserted into the […]

Diabetes affects approximately 4 million Canadians. Diabetes is associated with increased risk of heart failure, which is also substantially more common after a heart attack. Patients with diabetes are particularly vulnerable due to the combination of these risk factors. As a result, risk models that can identify diabetes patients who are at the greatest risk […]

The surgical practices involving fat are constantly evolving at the cutting edge of technology. Procedures involving fat manipulation, such as liposuction, contain a degree of subjectivity which is mainly guided by the surgeon’s visual or tactile perception of the underlying fat. This lack of subjectivity raises an important issue regarding the surgeon’s ability to replicate […]

The determination of HLA (Human Leukocyte Antigen) is of crucial importance for hematopoietic stem cell transplantation. The wide variability of the HLA system has some progressive advantages, but can make the search for compatible donors more complex for specific populations. While populations in the regions of Quebec were characterized several years ago for the HLA […]

Transplantation is the preferred treatment for patients whose kidneys have failed. There is an ever-growing gap between patients in need for a transplant and available donors. In response to this need, there has been an increase transplantation of donors who experienced circulatory determined death (DCD). However, many potential DCD donors fail to end up in […]