One of the goals of modern bioanalytical chemistry is the simultaneous (multiplexed) detection of multiple biomarkers in individual cells. Biomarkers are defined as characteristic proteins, genes, or small molecules that can be measured and evaluated as indicators of normal biological or pathological state of a cell. Mass cytometry is a recently developed technique developed by […]

Microfluidic systems, also known as “lab-on-a-chip devices”, take advantage of physical forces at the microscale to offer precise control and manipulation of fluids in micron-sized geometries. While these systems promise to revolutionize the life sciences industry, rapid fabrication of these devices during technology development remains a challenge, particularly the critical bonding step between thermoplastic parts. […]

Society uses thousands of chemicals and the potential risks to humans and the environment for the vast majority of these chemicals are largely unknown. It is not feasible to measure all of the chemicals and there are substantial data gaps; therefore, models are required to screen and evaluate chemicals for potential exposures and risks to […]

The proposed research will develop enhanced clustering and segmentation algorithms of high dimensional data. Cozumo Technologies, a world leader in the real-time capture and transmission of point-of-sale customer data, will use the research to improve their existing models of customer segmentation and offer generation. It is clear that real-time handling of big data represents a […]

Regional and municipal partners spend resources, time and effort securing and protecting their natural heritage systems. Roadways act as barriers restricting movement of plants and animals, degrading habitat for many species, and increasing mortality affecting the quality of these natural heritage systems. The intern will investigate methods, techniques and technologies that can be used to […]

Digital Tomosynthesis (DTS) is an innovative imaging modality that provides 3D reconstructed images of inner organs, using conventional digital x-ray equipment. The image slices are reconstructed from a series of projection images acquired as the x-ray tube moves around the patient in a limited angle path. DTS improves the sensitivity of lesion detection, due to […]

Unmanned aerial vehicles (UAVs) provide a cost-effective and low-risk airborne platform for scientific and surveillance equipment. Due to the variety of instrumentation that they can carry, UAVs have enormous potential for use in a range of commercial and military sectors. However, their small size and low speed brings about aerodynamic challenges that are not present […]

The Independent Electricity System Operator (IESO) coordinates electricity generation and transmission to ensure a reliable and stable electricity supply for the province of Ontario. Human operators monitor the power grid with the help of automated energy management systems. Increasing amounts of data, electricity demand, and renewable generation mean these operators need new tools to help […]

This research project will investigate retirement planning among academic physicians within the Department of Medicine (DOM) at the University of Toronto. The overall objective of this project is to investigate the range of perspectives held by members of the DOM about retirement and to develop a later career transition assessment tool that will facilitate institutional […]

The project seeks to provide a program evaluation of the Girls E-Mentorship Innovation (GEM) youth mentoring program. GEM’s program is a socially innovative approach linking high school aged girls with successful professional leaders in the employment sector, to support the development of positive attitudes and future career attainment. Using mixed methods, this project develops key […]

Recent studies show that chronic stress levels have increased by 30% in the last 3 decades[1]. The objective of this project is to place humans at the center of a new mobile-based platform called the Life Optimization Engine (LION). The goal is to optimize human performance via self-modulation through physiological feedback programs. LION will use […]

Currently, when man-made objects in orbit around the Earth need to be disassembled or repaired, a humancontrolled robotic manipulator is used. The object in question is often not designed to be modified in this manner, and only 1 in 4 human operators at MDA (the partner organization) are able to successfully complete these notoriously challenging […]