Mine Revegetation in the Yukon

The mining industry is one of the leading sectors of the Yukon economy. Mining companies are committed to restoring the land affected by mining activities to meet closure plan requirements. Revegetation of impacted sites is a challenge all mining companies face in sub-arctic regions because: 1- Lack of knowledge regarding which plants to use for […]

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Targeting SARS-CoV-2 (COVID-19) methyltransferases (nsp10-nsp14 and nsp10-nsp16 complexes) toward developing small molecule antiviral therapeutics

COVID-19 pandemic has brought the world to standstill with more than 3 million people infected and more than 200 000 mortality so far. It has literally brought the health care systems in many countries to the breaking point, if not beyond. The economic consequences have been devastating with millions of people out of work. We […]

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A 20 minute molecular diagnostic of COVID-19 within a “swab”

The research project will find optimal conditions for instrument-free, fast, and sensitive/specific detection of pathogen (COVID-19). The project is composed in two units(IU), each module within IU is offering independent technical solution for the current bottleneck in diagnostics industry. The first module is temperature-based denaturation of biological sample, coupled with nucleic acid-based detection (IU1). The […]

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Therapeutics and Catalysts for the COVID-19 Pandemic

Overcoming the COVID-19 pandemic will require a multi-pronged therapeutic approach that will draw on the expertise of biochemists, virologists, medicinal chemists and synthetic chemists. First-line tactics directly attack the virus itself. This will be done in the form of small-molecule antivirals that inhibit the development of virus particles during infection and replication. Secondary effects of […]

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PGX-processed yeast beta-glucans as an inhalable immunomodulating therapeutic for COVID-19 patients

While many people who acquire COVID-19 experience only minor symptoms or are completely asymptomatic, others (~20% of patients) experience a severe form of the disease associated with a phenomenon called a cytokine storm, an undesirable immune response that ultimately results in the deposition of fibrotic tissue in the lungs that causes the breathing difficulties and […]

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Machine Learning for Cancer Treatment Plan Benchmarking

Oncology specialists are few in numbers and cannot be present within every hospital or clinic providing their guidance and support. There are institutions in this world with oncology experts that can provide the best possible care and the knowledge of these experts is stored in medical case files within the hospital. With the power of […]

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Brainstem and cerebellar seizures: novel measures, modulations, and relationship to SUDEP

Epilepsy-related sudden death occurs following uncontrolled recurrent seizure which are usually non-responsive to antiepileptic drugs. These patients found dead in bed usually following heart and respiratory arrest. It is not known whether seizure-affected brain regions regulating cardiorespiratory function play a role in this complication and if so, what is the mechanism underneath in order to […]

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Charging/Discharging Mechanisms of Manganese Oxide Positive Electrodes in Zinc-Ion Batteries

Public awareness of global climate change resulting from greenhouse gas emission has led to increasing utilization of renewable energy sources such as wind and solar. These sources are inherently intermittent in nature, necessitating effective methods of storing power for later use. Zinc-ion batteries (ZIBs) are a promising candidate, since zinc is widely available and inexpensive. […]

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Radon: Building a BC Based Response – Year two

Radon is a cancer-causing radioactive gas produced by the natural decay of uranium in rocks and soils. Radon can enter buildings and reach high levels in indoor air (Khan and Gomes, 2017). It is the second-leading cause of lung cancer (after smoking). killing approximating 3200 Canadians a year (Chen et al. 2012). High radon concentrations […]

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Forced Air Ozone Reactor and Advanced Oxidative Process as an Alternative to Post-harvest Washing for Decontaminating Fresh Produce – Year two

The project will develop aqueous-free systems for decontaminating (i.e. inactivation of human pathogens and spoilage microbes) fresh produce that can be applied individually or sequentially. The first intervention is based on a forced-air ozone reactor that introduces the antimicrobial gas through the bed of produced at a controlled flow rate. The advantage of the method […]

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Enzymatic nano-immobilisation facilitated by 2D materials for antifouling coatings – Year two

Enzyme immobilisation is crucial for preserving the enzyme activity while enabling the enzymes to be recovered and reused for multiple applications in biocatalysis. However, immobilisation can change the structure and functionality of enzymes. Therefore, immobilisation of enzymes needs to be carefully investigated and controlled at fundamental levels. The emerging two-dimensional (2D) materials, such as graphene […]

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Development of easy-to-prepare pulse-based meals for consumption by office workers to combat the negative health consequences of a sedentary work environment – Year two

The project will involve the development of seven “pulse-based” lunches, which are designed to be easy to prepare (i.e. “out of the package”) for people in a typical busy office work environment. Pulses include non-oil legumes such as lentils, chickpeas, beans, and peas, which are a major component of the Canadian agricultural industry and an […]

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