Investigation into molecular mechanism of CRV431, a cyclophilin inhibitor, for anti-fibrotic and anti-oncogenic potential in various animal models

Various liver disorders such as fatty liver, liver fibrosis, liver failure and liver cancer, are major healthcare burden and associated with high rate of mortality. Once fatty liver or fibrosis progress to cirrhosis or liver failure, its treatment is challenging due to lack of an effective treatment. Currently available treatment for liver cancer is few […]

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The correlation and validation of functional markers and biomarkers for m/sTBIpopulations during simple and complex tasks – Year 1

This project aims to develop and validate markers for adaptive neurological performance therapies for persons with moderate-to severe traumatic brain injury (m/sTBI), with the purpose to further develop clinical paradigms for at-risk populations. In order to accomplish this, we have formed a collaboration between two Universities (Université Laval and McGill University) and two industrial partners […]

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An integrated system for gear condition monitoring and predictive maintenance

The management and reliability analysis of gear-driven rotating equipment is critical for the mining industry. The current maintenance practice employs non-destructive inspection methods to perform the assessment of health status. However, the assessment requires the machine under inspection to be shut down for the duration of the inspection. The associated cost is high. An ideal […]

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Design of Novel Catheter Systems for Local Drug Delivery and Cryogenic Lung Biopsy

Balloons have potential benefits over stents for localised drug delivery. The activities in this proposal will aid the development of a dual balloon catheter system. By the end of the internship, the balloon catheter design will be completed and frozen in anticipation of pre-clinical studies. The gold standard for diagnosis of interstitial lung disease is […]

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Evaluating the impact of culturally-sensitized brokerage or coaching on refugee newcomers’ nutritional acculturation in a pilot program

Refugee newcomers tend to experience “food” culture shock and are at greater risk of food insecurity due to inadequate social programs. Hybrid social programs may help boost refugee newcomer confidence through knowledge exchange during intercultural culinary experiences. Therefore, this project aims to: First, promote effective cultural brokerage between community sponsor groups and refugee newcomers; Second, […]

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Toward Net Zero Transportation – Validating environmental benefits of Hydrogen Internal Combustion Engine Vehicles

Hydra Energy Corporation Commercial Demonstration Project based in Prince George, British Columbia 12.4 MT/day of waste hydrogen will be captured, purified and transported to an onsite hydrogen refueling station from which Class 8 tractor-trailer truck fleets will refuel daily. Hydra’s demonstration project can provide a significant reduction in fleet greenhouse gas(GHG) emissions, Particulate Matter and […]

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Wireless charging based on capacitive-inductive resonance

This project is about a novel chip-based wireless power transfer system. Its integrated and flexible design eliminates the need for power cables for any DC device in homes, offices, parkades and power generating facilities. Unlike existing solutions, the system operates simultaneously with multi electricity requirement devices, has extended range, generates no heat, can transfer power […]

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“Transit Gender Sunshine List”: Assessment of Representation of Women as CEOs and Directors of Canadian Transit Systems

CUTRIC, in partnership with the University of Windsor are seeking greater understanding of the barriers to participation which have resulted in the low representation of women within the leadership ranks of Canadian transit systems. To better understand this lack of representation, a literature review will be conducted to ascertain what knowledge exists in this field […]

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Hydrogel Ionotronic Solar Cell

Solar power currently makes up a tiny fraction of all global energy needs. The current silicon based solar cell technologies which on average operate at around 15-17% efficiency have low likelihood of being a total fossil fuel replacement. They have very slow energy payback, their mass production cost savings are hitting a wall, and they […]

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The use of an affect-based music selection algorithm and embedded auditory beat stimulation as an intervention for high-anxiety populations

Chronic anxiety is a growing psychological disorder worldwide and in Canada. Even when anxiety presents at pre-clinical levels, it can be disabling. Anti-anxiety drugs have many adverse side-effects. In some cases, listening to music decreases anxiety more effectively than anti-anxiety drugs. Furthermore, some evidence suggests that curating a music selection as a function of the […]

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Noninvasive blood glucose monitoring system by midinfrared spectroscopy

More than 400 million people are suffering from diabetes mellitus in the present world. Till date, there is no cure for diabetes; however, it can be controlled by regulating the sugar intake in blood. Hence, diabetic patients need to monitor their blood sugar level regularly for few times a day. The conventional techniques are invasive […]

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Going On-line with Cognitive Rehabilitation: Testing and Implementing Web-based Goal Management Training at Clinical and Commercial Levels – Year two

Goal Management Training® (GMT) is a Baycrest cognitive intervention that has been studied extensively, applied clinically, and manualized into kits for clinicians that have been commercially available since 2012. GMT targets executive functions, a collection of higher-level abilities involved in planning, organization, strategy, and inhibition. Executive impairment can be seen in normal aging as well […]

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