Lipid-based nanoparticular drug formulations are a successful technique to enable targeted treatment. The Canadian company Precision Nanosystems Inc. (PNI) develops the innovative instrument family NanoAssemlr for lipid nanoparticle preparation based on microfluidics. These instruments are fast, easy-to-use and provide a high batch-to-batch reproducibility and quality. Recently, we developed a novel lipid nanoparticle formulation with the […]

Global pollution emissions contribute to climate change and are damaging to health. In many industrial applications that produce particulate matter, devices such as cyclones are used to separate and capture the particles from the exhaust gas. However, these do not capture the very small, but hazardous, particles and so expensive and energy-intensive secondary systems have […]

One of the most destructive natural disasters that Canada could experience is a major earthquake affecting a highly-populated area. A 2013 study commissioned by the Insurance Bureau of Canada estimated that a magnitude 9.0 earthquake in British Columbia, and a magnitude 7.1 earthquake in the Quebec City-Montreal-Ottawa corridor would result in financial losses of almost […]

Benefit payments totaled 2.5 billion dollars for Ontario workplaces in 2015. The most common injury resulting in a lost time claim was a strain or sprain – indicating despite massive efforts to reduce musculoskeletal injuries by ergonomists, these issues still have a significant financial burden on the economy. An easy-to-use, readily available, and automated physical […]

In this research, a new approach to model Frequency Dependant Network Equivalent (FDNE) will be introduced and implemented in PSCAD/EMTDC. FDNEs are used to accelerate and reduce the size of unnecessary part of the network under simulation. The new approach utilizes Brune’s network synthesis and Tellegen’s extension to create a multiport network whose impedance is […]

Forage nutritive value is a key component of profitable dairy production with forage fiber concentration and digestibility being critical, as high quality forages can reduce requirements for high-cost concentrated feeds. One approach and new technology developed to increase forage quality has been the release of high digestibility/lowlignin alfalfa cultivars, as alfalfa is the main forage […]

Oil spills pose both acute and chronic hazards to ecosystems and require effective and timely treatment. As large quantities of crude oils are transported across and in the proximity of oceans. rivers. and other waletways, it is especially important to be prepared for spills into water. The dynamic and variable character of aquatic environments especially […]

Many of those dealing with anxiety and/or depression are frequently in the care of a friend, partner, or family member known as an informal caregiver. This important role can be very taxing both physically and psychologically, yet few resources are available to specifically target individual caregivers’ needs. The proposed project will contribute to our understanding […]

The research project would involve developing and executing an experimental program to optimize the application of electrokinetic dewatering technology for oil sands tailings called EKS-DT developed by ElectroKinetic Solutions (EKS). This research will involve conducting a series of high priority experiments for process optimization and innovation. Three main research categories involving electrokinetic tailings consolidation modelling, […]

The strong tidal currents that make in-stream tidal energy possible, are also challenging to work in since they are also very turbulent. As the flow passes over the rough bottom and shoreline variations, eddies are generated over a wide range of scales. These eddies (i.e. turbulence) create fluctuating forces on tidal turbine blades and their […]

Chronic neuropathic pain affects millions of Canadians for which the government spends ~$6 billion a year on treatment. It is therefore imperative to find new therapies with few side effects and high therapeutic efficacy. This study will examine the therapeutic properties of cannabidiol (CBD), which is a non-intoxicating component of cannabis. Studies have shown that […]

Throughout much of North America moose populations are in decline and Manitoba is no exception. This project will determine what factors promoting occupancy and abundance at local and regional scales in Manitoba; and subsequently identify the most efficient way to monitor moose populations in relation to local and regional factors, such as hydroelectric power transmission […]