Les blessures traumatiques constituent un fardeau considérable pour les familles, les collectivités, l'industrie et le système de santé. De plus, le risque de blessure grave, surtout parmi les jeunes et les personnes âgées, est d'autant plus important lorsque ces personnes sont défavorisées. L'étude des liens entre le milieu et les blessures est complexe, puisque les […]

L’une des principales raisons de la régionalisation des soins de santé en Colombie-Britannique est de consacrer plus de ressources aux soins directs aux patients et moins à la bureaucratie et aux chevauchements. Une composante essentielle de cette approche systémique est de fournir à des établissements choisis les ressources dont ils ont besoin pour traiter les […]

Ibrutinib has proven to be very effective in newly diagnosed and relapsed chronic lymphocytic leukemia (CLL) patients. However, it can cause certain side effects that can lead to early discontinuation of treatment and worse outcomes for patients. The goal of this study is to determine the frequency of side effects in the “real-world” associated with […]

Among the many significant effects of the novel coronavirus 2019 (COVID-19), Vancouver General Hospital’s (VGH) Department of Psychiatry has observed the impact of the pandemic on the mental health of patients and providers. These circumstances have created unprecedented demand for decisive and rapid action to avert hospital admissions related to mental health, maximize efficiency within […]

The opioid epidemic is a serious health crisis and opioid treatment strategies are at the forefront of efforts to tackle this crisis. Replacement therapy is the current approach taken using medications such as methadone. To be more effective, the dosage needs to be tailored to individual tolerance which requires a point-of-care type analytical measurement of […]

We propose to develop a novel, clinically relevant MRI based technique for prostate cancer detection. We also propose to develop a novel reporting system that would be more accurate and easier to use by the radiologists. The new technique will be first developed on a research MRI scanner at UBC, and subsequently implemented on the […]

Basal cell carcinoma (BCC) is the most common cancer type. Although it can be surgically removed, to confirm the clean removal by histology is time-consuming, which complicates the treatment and results in many incomplete removals. We propose to develop a special microscopy imaging platform that can image the skin tissue directly without sectioning and staining. […]

Inflammatory Bowel disease (IBD) affects over 200,000 Canadians. Individuals with IBD have significantly greater risk of developing colorectal cancer. Unfortunately, the screening for colorectal cancer that is currently provided to the general population is inadequate for this group. White light colonoscopy is currently the gold standard but is challenging, as lesions are sometimes difficult to […]

Radiodermatitis is a group of skin reactions that occur as a result of radiation therapy. It is a significant health challenge as approximately 70% of all cancer patients receive radiation therapy and approximately 95% of them experience radiodermatitis. Patients with radiodermatitis experience redness, itchiness, pain, scaling, and weeping or crusted wounds. Importantly, radiodermatitis can impede […]

Obstructive Sleep Apnea (OSA) is an important disease characterized by recurrent blockages of the upper airway during sleep leading to breathing cessations (up to 100 times per hour); OSA is common and is widely under-diagnosed. OSA might cause cancer or lead to cancer progression, potentially mediated through low oxygen levels; however, evidence for this association […]

Spinal cord injury (SCI) results in severe paralysis, for which there are no effective treatments. Advanced technologies, however, can play an important role in assisting in the diagnosis, monitoring, and treatment of SCI patients who suffer many impairments beyond the loss of voluntary muscle control. In this proposal, we will develop and apply innovative technologies […]

The main goal of this research project is to study if a protein named SEMA3C can be a biomarker for early detection of an aggressive and lethal form of prostate cancer, named Double Negative Prostate Cancer (DNPC). To test if SEMA3C is a contributing factor in the progression of DNPC, we will compare SEMA3C level […]