Chronic Obstructive Pulmonary Diseases (COPD) is a lung disease that cause a lot of suffering to the Canadian population. To accelerate the drug discovery process, an old blood pressure lowering medication was tested to block the progression of COPD. A patient study showed that the old medication did provide some protective effect to the lung […]

Degenerative brain diseases, such as Alzheimer’s disease and Parkinson’s disease remain incurable despite intense research over decades. Progranulin, a protein that was identified and characterized in our laboratories and it has been shown to inhibit the development of Parkinson’s-like and Alzheimer’s-like symptoms in experimental models in mice by the partner organization Neurodyn. We believe that […]

Vaccines are one of the most important medical breakthroughs, proactively saving millions of lifes and reducing human morbidity. Yet there remains a need to make current vaccine formulations more effective and affordable, which requires testing and optimizing new formulations. In addition, there remains diseases for which there are no efficient vaccine. To develop and test […]

Considerable advances in geological and rock engineering mapping methods using both conventional and remote sensing techniques have occurred over the last decade. The primary objective of the proposed research is to further develop the use Virtual and Mixed Reality (VR/MR), techniques in improving structural geological and rock mass field data acquisition. New uses of MR […]

Implanted medical devices have dramatically improved the lives of millions of patients worldwide. However, in many cases, the body’s immune system rejects these devices and encapsulates the implant in fibrous scar tissue. This reaction is most detrimental to sensors for continuous monitoring and treatment of chronic conditions such as diabetes and those of the central […]

The research seeks to develop an easy to use and program SDK in the Unity software framework for the design and integration of expressive haptic effects for a distributed series of worn haptic actuators. The project’s central objective is to develop a cross platform composition tool for designers that makes it easy to integrate haptic […]

In the steelmaking industry, process control models need to be based on a sound physical understanding of the process but should also account for many uncertainties due to the nature and complexity of the environment in which the process is carried out. As a result, it is crucial to extract useful process control information from […]

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in […]

The project will provide an opportunity to address key challenges related to user expectation of Automated and Connected Electric Shuttles. That is, the project will serve to advance the understanding of user perception and experience of smart shuttles in Canada. This technology is increasingly often being tested in pilots across Canada and it is critically […]

Over the past three decades the time it takes for clinical laboratories to diagnose an infection has decreased from two weeks for culture to 3 hours for DNA testing following the introduction of large, automated bench top equipment. Despite this tremendous improvement, three hours is still too slow to allow rapid and accurate diagnosis of […]

Heart disease is the main reason of death worldwide. One way to understand better and detect heart diseases without need for biopsy via surgery is by using medical imaging such as magnetic resonance imaging (MRI). Cardiac magnetic resonance is a specific kind of MRI which allows great visualization of inner parts of the heart and […]

Conventional mining activities are composed of four distinct operation coming together. These operations are called; drilling, blasting, loading and hauling. As being the first step in this chain of operations, drilling quality and preciseness is very vital for the success and effectiveness of remaining components. Accurate drilling not only saves time to the company but […]