Targeting the GAS6/AXL Pathway in Acute Myeloid Leukemia Stem Cells with a Novel Combination Therapy

Blood cancer (leukemia) is common, with ~48,600 and 6,400 new cases expected in the United States and Canada respectively in 2016. The National Cancer Institute (US) calculated an overall 5-year survival rate of 56% for various blood cancers. This is because most current therapies are short-lived; drug resistance and relapse pose significant clinical problems. Life-long […]

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Computer Vision and Deep Learning for Moderating Visual Content

Two Hat Security is a company that develops next generation moderation tools for social networking apps. Since visual content (e.g. images, videos) is one of the most important types of data shared by social networking apps, an important problem for the company is to identify images/videos that are offensive or inappropriate. For example, certain images/videos […]

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Flow in business: Facilitating Flow in Virtual Reality trials and exploring the outcomes for product evaluations

Flow, the psychological state of being totally absorbed into an activity, has been suggested to be an important topic for future research as it represents ‘optimal experience.’ This research seeks to understand 1-how to facilitate flow while engaging with virtual reality products and 2-the outcomes of experiencing flow in regards to attitudes towards virtual reality […]

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Development and characterization of composites

In this project, Global Heat Transfer Ltd. (GHT) partners with the Composites & Optimization research group at the University of British Columbia in the Okanagan in order to integrate additive manufacturing into GHT’s current production line. Fabrication of high-performance compact radiator cores through additive manufacturing (AM) will not only resolve some of the current radiator […]

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In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem […]

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Exploring home range and habitat use during the breeding season of the Bicknell’s thrush (Catharus bicknelli) in New Brunswick Clear-cuts

The Bicknell’s thrush (Cathurs bicknelli) is a rare songbird with the most restrictive breeding range in North America. The Bicknell’s thrush spends its summer months breeding in high elevation, stunted growth forests – a habitat that the species specializes in. In New Brunswick, there has been a documented population decline of 11.5% per year since […]

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Context-Aware Advertising Language Analysis and Modeling in Internet Display Ads

Internet display advertising is a substantially growing industry, where advertising spots are dynamically allocated according the product characteristics and the target audience. This is commonly seen on Facebook or Google. However, accurate audience targeting is still an enormous challenge in practice, and often evokes frustration for advertisers and users. However, with the rapid growth and […]

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Identifying the drivers of polar bear-human interactions

Polar bears are curious, and that curiosity often leads them into conflict with people. Park and wildlife managers across the Arctic need to understand why polar bears approach people and whether they do so because of human activities, a lack of sea ice, or a combination of both of these factors. Currently, this is not […]

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