Regulating Abnormal Connectivity in Posttraumatic Stress Disorder via Real-time fMRI Neurofeedback

Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural […]

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Ontario Primary and Mental Health Policy Decision Tool

The Ontario government provides healthcare funding to fourteen Local Health Integration Networks (LHINs) across Ontario. LHINs in turn are responsible for structuring health care delivery and allocating funds to best meet the needs of the population in the region. However, there are limited tools available to help LHINs evaluate the system-wide implications of proposed policy […]

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Study the Mechanism and kinetics of Electrochemical Conversion of CO2 to Ethanol: A Molecular Modeling Approach

Closing the carbon cycle by utilizing CO2 as a feedstock for producing new fuels such as Methanol and Ethanol is an appropriate intermediate step towards a carbon-free future. Recently some researches on new nano-catalysts have increased the hope of bringing this technology to the market. While the reaction mechanisms are not elucidated, the present study […]

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Carbon dioxide: Alternative solutions for conversion of captured liquefied CO2 into valuable fuels

The partner organisation, Sigma Energy Storage, develops energy storage by gas compression. This technology is based on the storage of electricity from intermittent energy sources, such as wind or solar power, and the recovery of unused electricity from diesel-based power sources located in remote communities not connected to the electrical power grid system. During the […]

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A Novel Combination Therapy to Target Primitive Acute Myeloid Leukemia Cells

Modern molecular targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute leukemia patients. This is largely due to the survival of some leukemic cells that possess unique properties and can cause treatment failure or relapse, warranting identification of new, distinct targets for improved therapies. In collaboration […]

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ABHD6 as a novel drug target for obesity, non-alcoholic fatty liver disease (NASH) and cardiovascular disease (CVD)

Obesity, type 2 diabetes (T2D) and heart diseases have skyrocketed. Controlling glucose usage and insulin balance can substantially decrease the morbidity and improve the quality of life in affected individuals. Dysfunctional insulin action and energy balance in the body is associated with excessive non-adipose fat storage, particularly in the liver, and elevated circulating lipids, which […]

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Disturbance thresholds and factors influencing community dynamics of epiphytic cyanolichens in Nova Scotia, with an emphasis on rare and at-risk species

The coastal wet mixedwood forests of Nova Scotia are globally important for lichen biodiversity, but several lichen species are now declining or endangered. This is concerning for forest managers, because forest companies may be subject to penalties if they inadvertently destroy the habitat of an endangered species. The causes of lichen declines are not fully […]

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Characterization of cell signaling in response to ultraviolet radiation after treatment with an oral skin-care supplement

Bend Beauty is a Halifax based company involved in the research, development, and marketing of oral natural health products for use in skin-care and anti-aging. Bend?s core product, Anti-Aging Formula, is a mixture of the active ingredients fish oil, borage oil, lutein, zeaxanthin, and vitamin D3. An eight-week human clinical study demonstrated this product increases […]

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