Characterizing lytic bacteriophages against pathogenic E. coli: receptor specificity, efficacy in vivo, and genomic analysis

Many facets of human life are affected by bacterial pathogens. Bacteria can cause both animal and plant diseases. Extensive use of antibiotics to contend with pathogenic bacteria has resulted in an increase of multi-resistance to antimicrobials. Even when antibiotics are used vigilantly, their application in poultry or other fields of animal production can lead to […]

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An order-reduced simulation framework for 3D multiscale geophysical electromagnetic problems

The goal of this research is to investigate the extension of upscaling and multiscale methods and their application to efficiently simulate (frequency-dependent and time-dependent) electromagnetic fields in geophysical scenarios that include metallic-cased boreholes and fractures filled with conductive/resistive fluids. Simulating this type of geophysical settings is quite challenging because they consider highly heterogeneous media and […]

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Exploring the Impact of Housing-based Overdose Prevention Interventions on People who use Drugs in Vancouver – Year two

Canada is amid an opioid epidemic, with governments declaring overdose public health emergency. Drug-related overdose mortality in British Columbia reached a record high in 2017, with over 1400 deaths. In response, novel overdose prevention interventions (OPI) have been implemented, including: overdose prevention sites in which people can inject drugs under supervision; and, naloxone training and […]

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Modeling of the Wear Performance of Carbide-Based Overlays and Coatings

Surface degradation during Oil & Gas and Mining operations in the Province of Alberta are pervasive. This has resulted in extensive research and development activities into the development of advanced surface modifications that are based on overlays and coatings. Most research effort has focused on materials selection, fabrication, and optimization of wear performance of those […]

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Regulating Abnormal Connectivity in Posttraumatic Stress Disorder via Real-time fMRI Neurofeedback – Year two

Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural […]

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Measuring Social Progress on Urban Aboriginal People: Construction and Application of a Composite Index of Quality of Life – Year Two

As Aboriginal people increasingly migrate to urban areas, it has become imperative to promote their socioeconomic engagement in the destinations. While there has been increasing research focuses on Aboriginal peoples’ quality of life (QoL) few studies explicitly measure Aboriginal people’s QoL based on a shared understanding of what QoL really means to Indigenous peoples and […]

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Improving Powder Performance by Development and Optimization of Industrial Lubricants and Mixing Technology for Powder Metallurgy – Year two

Ideal flow, high-volume Powder Metallurgy (PM) manufacturing can achieve uniform, consistent filling of die cavities, leading to high productivity, low rejection rates, improved part integrity and consistent part dimensions. The type and amount of lubricant, size and shape of lubricant particles, mixing parameters and certain environmental conditions all significantly influence the flow characteristics and apparent […]

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Study of Indian and Ukrainian legal frameworks regulating biofertilizers and biocontrol agents in reference to Canadian microbial products – year 2

This research aims at primarily analysing the legal frameworks regulating biofertilizers and biopesticides (also known as ‘biologicals’) in India and Ukraine. After studying and analysing the legal frameworks, and barriers in registration procedures for R&D, trial, transfer, trade, transport and storage of new molecules and microbial strains of agro-biologicals, a draft of alternative regulations will […]

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