Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural […]

Drug resistance of medically relevant microorganisms poses a grave threat to human health and has severe economic consequences. Fungal pathogens pose an additional complication as they are closely related to their human host. Current therapies to treat fungal infections are limited and drug resistance has already emerged in the clinic. We have conducted extensive research […]

In the health technology assessment (HTA) process, cost- effectiveness analysis gets more attention, however over last decade, the budget impact analysis (BIA) has certainly become more important to the subsequent steps, including the adoption decision. The first Canadian BIA Guidelines was published by Patented Medicine Prices Review Board (PMPRB) in 2007. According to the results […]

This project will involve an evaluation of a program to house people who have serious mental illness, and who have had experiences of homelessness. There will be two parts to this study. First, the study will examine how this program has been implemented. A study of the implementation of the program will provide information that […]

Considering the soot-free burning characteristics of DME/OME fuel, highly diluted intake charge can be introduced in order to realize ultra-low nitrogen oxides emissions. However, the ignition process of the highly diluted fuel/air mixture is difficult, and an unstable ignition process is detrimental to fuel efficiency and engine performance. In this project, innovative ignition systems including […]

The majority of mid-20th century high-rise concrete housing stock have reached the end of their first lifecycle in terms of structural integrity and environmental performance, and the urban planning ideals with which they were designed have made these neighbourhoods irrelevant to the contemporary culture of the city. Solutions for economical, structural, social and technological barriers […]

In this project, a series of highly efficient and highly selective multifunctional Guerbet catalysts are developed and will be investigated for the condensation of low alcohols to high alcohols in a continuous-flow reactor. Low energy density bioethanol and methanol will be upgraded to n-butanol and iso-butanol with high energy content comparable to gasoline with high […]

Corporations are under a lot of scrutiny, especially when they annually release their financial reports to the government. If a corporation makes a mistake, or if an employee submits fraudulent information, or if it appears that either is the case, then they risk being asked to amend the filing by the government, which will cause […]

The goal of the project is to gain insight into individuals’ reactions to an artificial intelligence (AI) product currently in development at Kiite. The product is designed to fulfill some of the role responsibilities typically occupied by a manager. Trust is an important factor in both leader-employee relationships and in user experiences with AI-based systems. […]

The industry partner of this project has an elevator modernization project that includes increasing the current speeds of their elevators by more than 30%. However, increase in speed is usually associated with increase in aerodynamic and lateral forces on the elevator cars, which can negatively affect ride quality and noise levels. The objective of this […]

Heart failure (HF) is one of the leading causes of hospitalization and rehospitalization in older adults, yet the majority of HF-related readmissions are preventable if patients can manage their treatment at home. One method to help patients who require extra assistance in following their treatment is through mHealth applications. However, these applications are not usable […]

The intent of this project is to demonstrate the GHG and electricity use savings of a range of low carbon heating, ventilation, and air conditioning (HVAC) technologies in the multi-unit residential building (MURB) sector. Technologies to be studied include: • ductless mini-split air source heat pumps (ASHP) • gas absorption heat pumps • smart thermostats […]