Drone Assessment of Winter Feeding of Climate Resilient Cattle

In the Climate Resilience Cattle project, we are combining the Red Angus, Senepol, Galloway, and Scottish Higland Bos taurus breeds with the objective of producing a novel synthetic breed called the Climate Master Composite. Thermally equipped drones will be autonomously flown to each individual animal using the GPS coordinates supplied by Virtual Fencing collars placed […]

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Fusarium avenaceum as a pathogen of cereals and pulses in Europe and Canada

Fusarium avenaceum causes Fusarium Head Blight, a devastating disease affecting cereal crops, and in Root Rot in pulses; diseases that significantly impact Canadian and European farmers. Different strains of F. avenaceum can harbor strain-specific biosynthetic gene clusters that produce mycotoxins which give rise to particularly virulent strains. In this context, the intent of this Globalink […]

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Conflict over noise in the city: the issue of motor vehicle noise in the city

The proposed research project focuses on investigating the growing problem of motor vehicle noise in urban environments, particularly how it affects residents’ physical and mental health, overall well-being, and willingness to live in densely populated areas. Through a combination of analysis methods involving interviews and fieldwork observations, the project will explore how residents experience and […]

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Using genotyping by sequencing to detect introgressed regions of genomic DNA in two Fundulus species

Species are delimited by barriers to reproduction, which can be caused by genetic incompatibilities that arise when isolated populations become two distinct species. Nevertheless, hybridization can occur when species are genetically similar enough to have few barriers to reproduction. If the hybrid offspring is viable and fertile, it can mate with either of the parental […]

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Investigating the effect of disease-causing TRNT1 mutations on cellular stress response: a pathway to treatment.

The proposed project aims to investigate the link between tRNA maturation and mitochondrial disease using yeast as a model system. Researchers from Carleton University in Canada will collaborate with experts from Comenius University in Slovakia to develop advanced gene-tagging techniques in yeast. This collaboration will allow for the creation of new reagents, tools, and technologies […]

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The loss of photosynthesis in green algae: a case study for ecological transitions

We propose to investigate the physiological and ecological factors driving the loss of photosynthesis in green algae and their transition to a permanent heterotrophic lifestyle. Autotrophs produce organic molecules (such as carbohydrates) from inorganic compounds (CO2), and photoautotrophs are reliant on sunlight to do this. Photoautotrophs are the primary producers of most ecosystems. Most of […]

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Violacein effects in mice Rho 264.7 cells

Violacein is a molecule naturally produced in some bacteria such as Chromobacterium violaceum. It has been shown that violacein has promising antibiotic, anti-tumor proliferation, anti-leishmanial and anti-fungal properties. Violacein is commercially available. However, it is very expensive. The objective of this proposed research study is to measure the effects of violacein produced by Escherichia coli […]

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Uncovering the cell type specific behavior of immune response in the chicken

This project will allow McGill University to be part of a larger-scale project focusing on the genetic expression variance in chickens, headed by the team at Aarhus University. Previous work has been done to categorize general gene expression across numerous tissues types, with the focus now shifting to better understand the drivers behind gene expression […]

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L2M – LigandQI: Empowering Drug Design with Quantum Information

Nearly 90% of drug candidates fail during the drug design and development process, resulting in exorbitant costs to bring a new drug to market. Our technology, LigandQI, addresses the critical shortcomings in current computational drug design programs by leveraging ab initio quantum chemistry to quantify ligand-receptor interactions with unprecedented accuracy. Unlike traditional methods, our program […]

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Élucidation des rôles de la voie hippo dans les adaptations physiologies de l’utérus bovin sous l’effet de l’oestrogène et de la progestérone dans un modèle in vitro d’explants utérins bovins

Une bonne compréhension des mécanismes impliqués dans la physiologie utérine normale est essentielle pour améliorer l’efficacité de la reproduction dans la production animale. L’utérus bovin est un organe dynamique dans lequel diverses adaptations morphologiques et physiologiques sont observées tout au long du cycle de l’œstrus, en particulier sous l’effet de la progestérone et des œstrogènes. […]

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Advancing Therapeutic Nanotechnologies: Quantitative Insights into mRNA-Lipid Nanoparticles

Leveraging the groundbreaking research of Dr. Sabrina Leslie and her team, this project represents a significant stride towards mastering the analysis of mRNA within Lipid Nanoparticles (LNP). Building upon our novel findings, published in ACS Nano (2021), which introduced the first quantitative imaging technique for RNA-LNP formulations, we aim to precisely quantify mRNA molecules in […]

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Understanding habitat and social factors as drivers of sexual segregation in Bighorn Sheep (Ovis canadensis)

This project plans to unravel the relation between habitat characteristics and social dynamics that influence sexual segregation in Rocky Mountain bighorn sheep (Ovis canadensis). We will evaluate environmental and behavioural factors to better understand habitat preferences and social interactions that drive observed seasonal social and habitat segregation in bighorn sheep. The results of this study […]

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