Novel imaging approaches to understand heart function

The most common sustained cardiac arrhythmia is atrial fibrillation (AF), affecting 2-3% of the general population. If left untreated, arrhythmias can lead to heart failure, stroke, or sudden death. A better understanding of AF mechanisms is needed to improve our understanding of disease pathogenesis and create new therapeutic tools. We have developed a zebrafish model […]

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Trait diversity across forest biomes

Trait-based mass-ratio and complementarity effects shape community structure, population dynamics, and ecosystem functioning. A question remains on how these processes interact in maintaining forest biomass along the elevation. Leaf element contents will be used to test these interactions since they are surrogates of ecosystem functioning. An extensive survey was conducted during 2017-2018 along a wide […]

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Cortical microstructural asymmetry in the human brain: laminar differentiation, organization, and heritability

Lateralization is one of the key principles of human brain organization. With a background in neuroimaging analysis of brain inter-hemispheric differences, the applicant Bin Wan will conduct his project in a Canadian research group which focuses on multimodal neuroimaging data. The intern will help with data acquisition of 7 Tesla MRI data in healthy individuals […]

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Effect of exercise training on the human skeletal muscle proteome, phosphoproteome, and proteodynamics

Generally, resistance exercise increases muscle mass and strength, whereas endurance exercise increases the capacity to use fuels and fatigue resistance. In both cases, skeletal muscle translates the physical and biochemical stresses of exercise into morphological and metabolic adaptations, with the adaptations improving one’s ability to perform the corresponding type of exercise. This concept is known […]

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Élaboration de nouveaux microgels photothermiques

Le projet consiste à utiliser un microgel déjà existant constituer d’un polymère ainsi que des particules d’or. Ce microgel présente des caractéristiques de gonflement réversible. Ces gonflements peuvent être maîtrisés par l’irradation à la lumière du microgel. A partir de ce microgel, on souhaite y greffer des nouveaux polymères. Les greffages auront lieu soit directement […]

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Statistical aspects of Optimal Transport

This proposal explores the use of optimal transport in statistics and machine learning as well as develop one simple application in chemistry. Optimal transport is a well established mathematical field whose actors have gone to receive the most prestigious recognitions. Its inventor, Leonid Kantorovich, received the Nobel Prize in Economics. Cedric Villani, who wrote the […]

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Effet de la salinité sur l’efficacité de traitement de l’azote ammoniacal par les microbulles d’ozone

L’étudiant étudiera l’influence de la salinité sur l’efficacité de traitement de l’azote ammoniacal présents dans les effluents miniers par les microbulles d’ozone. Cette étude permet d’avancer l’identification des facteurs qui peuvent influencer ce type de traitement qui a montré son efficacité pour le traitement des eaux minières dans des conditions climatiques froides.

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The relationships among phytohormones and benzylisoquinoline alkaloids during early development of Papaver rhoeas L.

Benzylisoquinoline alkaloids (BIAs) constitute a diverse class of plant secondary metabolites (SM) that exhibit a myriad of pharmacological activities. While there have been tremendous efforts to chemically synthesize high-value BIAs, this approach is not economical due to their complex chemistry. Also, production of BIAs using traditional means also has several drawbacks. An alternative is the […]

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Characterization of the function of Gbp2 and Tcg1 proteins as candidate telomeric proteins of the yeast Yarrowia lipolytica

Telomeres are nucleo-protein structures at the ends of chromosomes that are essential for preserving genomic integrity. Although many protein components of telomeres are known, their nature was studied in a relatively narrow range of organisms. The proposed research is aimed at the identification of novel players involved in telomere maintenance in a nonconventional yeast species […]

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Testing the paternity hypothesis for male care in Rwenzori Angolan colobus

Most mammals require care from older individuals during early life. Mothers tend to be the primary caregivers during this time, but in some mammals, notably social carnivores, rodents, and primates, care can be provided by conspecifics. In most primate species, allomothers tend to be female, making infant care by males a rare behaviour. Recently, we […]

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Ultrastructure of GABA, glycine and glutamate co-transmitting synapses in the immature brainstem

The synapse forms the core unit of information transfer in the brain, and most brain disorders, both developmental and degenerative, are caused by synaptic dysfunction. Understanding synaptic organization is therefore central to both basic research and health research in neuroscience. Our still-evolving understanding of the synapse includes relatively recent recognition that many synapses use multiple […]

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