Yeast will be used as a model to investigate inherited mitochondrial diseases in this research project, with a particular emphasis on the functional role of the Pic2 protein. Although initially identified as a mitochondrial phosphate transporter, recent studies have proposed its involvement in copper transport. To gain insight into Pic2 and its function, a combination […]

Most neurotraumas affecting the control of movements are partial, allowing some recovery of movement with time and rehabilitation. Motivation and persistence through this difficult process are crucial in mediating rehabilitation-dependent recovery, but are negatively affected by the physical and psychological challenges that accompany neurotrauma. We know that the reward network of the brain is involved […]

The developmental programming of an organism ensures reproducibility of organ shape and size with accurate robustness. But, how an organ knows when to grow and when to stop is a key question that remains inadequately addressed. Both genetics and mechanics play a role in the maintenance of organ reproducibility and robustness, especially in plants. Mechanical […]

Plants have several ways of defending themselves from plant pathogens including physical structures such as thick cuticles and defense hormones such as salicylic acid. The latter induces a cascade of plant defense responses that can ultimately lead to resistance. Similarly, to successfully invade their host, plant pathogens secrete a cocktail of proteins called effectors that […]

L’entraînement par intervalles de haute intensité (HIIT) permet d’améliorer les facteurs déterminants de la performance sportive. Toutefois, la prescription des HIIT est souvent basée sur des études dans lesquelles les femmes sont sous représentées ou même absentes. Pourtant, une compréhension des réponses physiologiques en fonction du sexe est cruciale pour permettre l’individualisation de la prescription […]

The most common sustained cardiac arrhythmia is atrial fibrillation (AF), affecting 2-3% of the general population. If left untreated, arrhythmias can lead to heart failure, stroke, or sudden death. A better understanding of AF mechanisms is needed to improve our understanding of disease pathogenesis and create new therapeutic tools. We have developed a zebrafish model […]

Trait-based mass-ratio and complementarity effects shape community structure, population dynamics, and ecosystem functioning. A question remains on how these processes interact in maintaining forest biomass along the elevation. Leaf element contents will be used to test these interactions since they are surrogates of ecosystem functioning. An extensive survey was conducted during 2017-2018 along a wide […]

Lateralization is one of the key principles of human brain organization. With a background in neuroimaging analysis of brain inter-hemispheric differences, the applicant Bin Wan will conduct his project in a Canadian research group which focuses on multimodal neuroimaging data. The intern will help with data acquisition of 7 Tesla MRI data in healthy individuals […]

The floral composition, including algae, of the Qazvin basin, is poorly known. This basin is located on a mountain range that is a very important place in the world for its biodiversity and endemism, generated by the geological and topographic complexity. In this project we will identify the diatoms (silica algae) that inhabit the Shahroud […]

Generally, resistance exercise increases muscle mass and strength, whereas endurance exercise increases the capacity to use fuels and fatigue resistance. In both cases, skeletal muscle translates the physical and biochemical stresses of exercise into morphological and metabolic adaptations, with the adaptations improving one’s ability to perform the corresponding type of exercise. This concept is known […]

Le projet consiste à utiliser un microgel déjà existant constituer d’un polymère ainsi que des particules d’or. Ce microgel présente des caractéristiques de gonflement réversible. Ces gonflements peuvent être maîtrisés par l’irradation à la lumière du microgel. A partir de ce microgel, on souhaite y greffer des nouveaux polymères. Les greffages auront lieu soit directement […]

This proposal explores the use of optimal transport in statistics and machine learning as well as develop one simple application in chemistry. Optimal transport is a well established mathematical field whose actors have gone to receive the most prestigious recognitions. Its inventor, Leonid Kantorovich, received the Nobel Prize in Economics. Cedric Villani, who wrote the […]